Literature DB >> 16872029

Adherence to clinical guidance in the prescribing of oral antithrombotic medication in patients with atrial fibrillation.

M Savage1, M Teeling, K Bennett, J Feely.   

Abstract

BACKGROUND: Atrial fibrillation is the commonest cardiac rhythm disturbance and is an independent risk factor for stroke; however, use of oral antithrombotic therapy is reported to be suboptimal in clinical practice. AIM: The aim of the study was to evaluate the prescribing rates of oral antithrombotic therapy in patients with atrial fibrillation to determine if prescribing patterns reflected published clinical guidance.
METHOD: Patients with atrial fibrillation, admitted to hospital over a 12-week period were identified and their antithrombotic therapy regimen was analysed using statistical methods.
RESULTS: Although 87/100 patients identified were prescribed OAT, the regimen was suboptimal in 35 patients. Patients aged 75 years and older were more likelyto be receiving suboptimal oral antithrombotic treatment compared with younger patients
CONCLUSIONS: The benefits and suitability of oral antithrombotic therapy for patients of all ages need to be more comprehensively communicated to prescribers.

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Year:  2006        PMID: 16872029     DOI: 10.1007/bf03167949

Source DB:  PubMed          Journal:  Ir J Med Sci        ISSN: 0021-1265            Impact factor:   1.568


  18 in total

Review 1.  Long-term anticoagulation therapy for atrial fibrillation in elderly patients: efficacy, risk, and current patterns of use.

Authors:  D McCormick; J H Gurwitz; R J Goldberg; J Ansell
Journal:  J Thromb Thrombolysis       Date:  1999-04       Impact factor: 2.300

Review 2.  Antithrombotic therapy in atrial fibrillation.

Authors:  G W Albers; J E Dalen; A Laupacis; W J Manning; P Petersen; D E Singer
Journal:  Chest       Date:  2001-01       Impact factor: 9.410

3.  Treating individuals according to evidence: why do primary care practitioners do what they do?

Authors:  N Oswald; H Bateman
Journal:  J Eval Clin Pract       Date:  2000-05       Impact factor: 2.431

4.  Differences between perspectives of physicians and patients on anticoagulation in patients with atrial fibrillation: observational study.

Authors:  P J Devereaux; D R Anderson; M J Gardner; W Putnam; G J Flowerdew; B F Brownell; S Nagpal; J L Cox
Journal:  BMJ       Date:  2001-11-24

Review 5.  Self-monitoring of oral anticoagulation: a systematic review and meta-analysis.

Authors:  C Heneghan; P Alonso-Coello; J M Garcia-Alamino; R Perera; E Meats; P Glasziou
Journal:  Lancet       Date:  2006-02-04       Impact factor: 79.321

6.  Implementing evidence based medicine in general practice: audit and qualitative study of antithrombotic treatment for atrial fibrillation.

Authors:  A Howitt; D Armstrong
Journal:  BMJ       Date:  1999-05-15

7.  Impact of adverse events on prescribing warfarin in patients with atrial fibrillation: matched pair analysis.

Authors:  Niteesh K Choudhry; Geoffrey M Anderson; Andreas Laupacis; Dennis Ross-Degnan; Sharon-Lise T Normand; Stephen B Soumerai
Journal:  BMJ       Date:  2006-01-10

8.  Adverse outcomes and predictors of underuse of antithrombotic therapy in medicare beneficiaries with chronic atrial fibrillation.

Authors:  B F Gage; M Boechler; A L Doggette; G Fortune; G C Flaker; M W Rich; M J Radford
Journal:  Stroke       Date:  2000-04       Impact factor: 7.914

9.  National trends in antiarrhythmic and antithrombotic medication use in atrial fibrillation.

Authors:  Margaret C Fang; Randall S Stafford; Jeremy N Ruskin; Daniel E Singer
Journal:  Arch Intern Med       Date:  2004-01-12

Review 10.  Comparing the guidelines: anticoagulation therapy to optimize stroke prevention in patients with atrial fibrillation.

Authors:  Stanley G Rockson; Gregory W Albers
Journal:  J Am Coll Cardiol       Date:  2004-03-17       Impact factor: 24.094

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  3 in total

Review 1.  Stroke and Death Prediction with the Impact of Vascular Disease in Patients with Atrial Fibrillation.

Authors:  Abhishek Maan; Amir Y Shaikh; Moussa Mansour; Jeremy N Ruskin; E Kevin Heist
Journal:  J Atr Fibrillation       Date:  2012-06-15

2.  Performance of stroke risk scores in older people with atrial fibrillation not taking warfarin: comparative cohort study from BAFTA trial.

Authors:  F D R Hobbs; A K Roalfe; G Y H Lip; K Fletcher; D A Fitzmaurice; J Mant
Journal:  BMJ       Date:  2011-06-23

3.  Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient.

Authors:  Scott W Yates
Journal:  Int J Gen Med       Date:  2013-03-21
  3 in total

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