Literature DB >> 10323820

Implementing evidence based medicine in general practice: audit and qualitative study of antithrombotic treatment for atrial fibrillation.

A Howitt1, D Armstrong.   

Abstract

OBJECTIVE: To determine the extent to which implementation of an evidence based treatment, antithrombotic treatment in atrial fibrillation, is possible in general practice.
DESIGN: Audit and qualitative study of patients with atrial fibrillation and an educational intervention for patients judged eligible for antithrombotic treatment.
SETTING: South east England.
SUBJECTS: 56 patients with a history of atrial fibrillation.
INTERVENTIONS: Assessment and interview to ascertain patients' views on antithrombotic treatment. MAIN OUTCOME MEASURES: Number of patients receiving antithrombotic treatment.
RESULTS: Out of 13 239 patients, 132 had a history of atrial fibrillation of which 100 were at risk of thromboembolism. After the study, 52 patients were taking warfarin. Of the remaining 48 patients (of whom 41 were taking aspirin), eight were too ill to participate, 16 were unable to consent, four refused the interview, and 20 declined warfarin. Patients declining warfarin were inclined to seek a higher level of benefit than those taking it, as measured by the minimal clinically important difference. Qualitative data obtained during the interviews suggested that patients' health beliefs were important factors in determining their choice of treatment.
CONCLUSION: Patients' unwillingness to take warfarin seemed to be a major factor in limiting the number who would eventually take it.

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Year:  1999        PMID: 10323820      PMCID: PMC27873          DOI: 10.1136/bmj.318.7194.1324

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


  11 in total

1.  Predictors of thromboembolism in atrial fibrillation: I. Clinical features of patients at risk. The Stroke Prevention in Atrial Fibrillation Investigators.

Authors: 
Journal:  Ann Intern Med       Date:  1992-01-01       Impact factor: 25.391

2.  Non-valvular atrial fibrillation (NVAF)

Authors:  E Roderick; J Cox
Journal:  Br J Gen Pract       Date:  1997-10       Impact factor: 5.386

3.  A survey of atrial fibrillation in general practice: the West Birmingham Atrial Fibrillation Project.

Authors:  G Y Lip; D J Golding; M Nazir; D G Beevers; D L Child; R I Fletcher
Journal:  Br J Gen Pract       Date:  1997-05       Impact factor: 5.386

Review 4.  ABC of atrial fibrillation. Antithrombotic treatment for atrial fibrillation.

Authors:  G Y Lip; G D Lowe
Journal:  BMJ       Date:  1996-01-06

5.  Anticoagulation in patients with atrial fibrillation. GPs not prepared for monitoring anticoagulation.

Authors:  F Taylor; M Ramsay; J Voke; H Cohen
Journal:  BMJ       Date:  1993-12-04

6.  Guidelines on anticoagulant treatment in atrial fibrillation in Great Britain: variation in content and implications for treatment.

Authors:  R Thomson; H McElroy; M Sudlow
Journal:  BMJ       Date:  1998-02-14

7.  Atrial fibrillation and stroke prevention in the community.

Authors:  J E O'Connell; C S Gray
Journal:  Age Ageing       Date:  1996-07       Impact factor: 10.668

8.  Prevalence of atrial fibrillation and eligibility for anticoagulants in the community.

Authors:  M Sudlow; R Thomson; B Thwaites; H Rodgers; R A Kenny
Journal:  Lancet       Date:  1998-10-10       Impact factor: 79.321

9.  Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials.

Authors: 
Journal:  Arch Intern Med       Date:  1994-07-11

10.  Warfarin for atrial fibrillation. The patient's perspective.

Authors:  M Man-Son-Hing; A Laupacis; A O'Connor; G Wells; J Lemelin; W Wood; M Dermer
Journal:  Arch Intern Med       Date:  1996-09-09
View more
  49 in total

1.  Antithrombotic treatment for atrial fibrillation. Patients must be told full details of risks of treatment.

Authors:  G Peterson
Journal:  BMJ       Date:  1999-09-11

2.  Anticoagulation for patients with atrial fibrillation and risk factors for stroke. Warfarin reduces the risk by two thirds, but doctors still aren't prescribing it enough.

Authors:  S J Connolly
Journal:  BMJ       Date:  2000-05-06

3.  Anticoagulation to prevent stroke in atrial fibrillation. It's still not clear whether results in secondary care translate to primary care.

Authors:  D A Fitzmaurice; J Mant; E T Murray; F D Hobbs
Journal:  BMJ       Date:  2000-11-04

4.  Anticoagulation for patients with atrial fibrillation. Editorial may have overinterpreted data.

Authors:  N Dudley
Journal:  BMJ       Date:  2000-09-09

5.  Anticoagulation therapy for patients with atrial fibrillation.

Authors:  R G Hart
Journal:  CMAJ       Date:  2000-10-17       Impact factor: 8.262

Review 6.  Antithrombotic treatment in atrial fibrillation.

Authors:  G Y H Lip; C J Boos
Journal:  Heart       Date:  2005-09-13       Impact factor: 5.994

7.  Anticoagulation for atrial fibrillation.

Authors:  Michelle Greiver
Journal:  Can Fam Physician       Date:  2005-12       Impact factor: 3.275

Review 8.  Antithrombotic treatment in atrial fibrillation.

Authors:  L Kalra; G Y H Lip
Journal:  Heart       Date:  2006-09-04       Impact factor: 5.994

Review 9.  Patient values and preferences in decision making for antithrombotic therapy: a systematic review: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

Authors:  Samantha MacLean; Sohail Mulla; Elie A Akl; Milosz Jankowski; Per Olav Vandvik; Shanil Ebrahim; Shelley McLeod; Neera Bhatnagar; Gordon H Guyatt
Journal:  Chest       Date:  2012-02       Impact factor: 9.410

10.  Adherence to clinical guidance in the prescribing of oral antithrombotic medication in patients with atrial fibrillation.

Authors:  M Savage; M Teeling; K Bennett; J Feely
Journal:  Ir J Med Sci       Date:  2006 Apr-Jun       Impact factor: 1.568

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