| Literature DB >> 16870779 |
Emilia Cantón1, Javier Pemán, Macrina Sastre, Mónica Romero, Ana Espinel-Ingroff.
Abstract
Amphotericin B (AMB), micafungin, and caspofungin MICs, minimal fungicidal concentrations, and time-killing curves were determined in the presence and absence of 10% inactivated serum. AMB was the only agent with consistent killing activity (time required to achieve 99.9% of growth reduction was 2.1 to 3.2 h). The presence of serum enhanced caspofungin activity but lowered those of micafungin and AMB.Entities:
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Year: 2006 PMID: 16870779 PMCID: PMC1538680 DOI: 10.1128/AAC.00524-06
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191