Literature DB >> 16870473

SIGNATURE: a single-particle selection system for molecular electron microscopy.

James Z Chen1, Nikolaus Grigorieff.   

Abstract

SIGNATURE is a particle selection system for molecular electron microscopy. It applies a hierarchical screening procedure to identify molecular particles in EM micrographs. The user interface of the program provides versatile functions to facilitate image data visualization, particle annotation and particle quality inspection. The system design emphasizes both functionality and usability. This software has been released to the EM community and has been successfully applied to macromolecular structural analyses.

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Year:  2006        PMID： 16870473     DOI： 10.1016/j.jsb.2006.06.001

Source DB:  PubMed          Journal:  J Struct Biol        ISSN： 1047-8477            Impact factor:   2.867


  87 in total

1.  Identifying conformational states of macromolecules by eigen-analysis of resampled cryo-EM images.

Authors:  Pawel A Penczek; Marek Kimmel; Christian M T Spahn
Journal:  Structure       Date:  2011-11-09       Impact factor: 5.006

2.  The complex of tmRNA-SmpB and EF-G on translocating ribosomes.

Authors:  David J F Ramrath; Hiroshi Yamamoto; Kristian Rother; Daniela Wittek; Markus Pech; Thorsten Mielke; Justus Loerke; Patrick Scheerer; Pavel Ivanov; Yoshika Teraoka; Olga Shpanchenko; Knud H Nierhaus; Christian M T Spahn
Journal:  Nature       Date:  2012-05-06       Impact factor: 49.962

3.  Subunit interactions in bovine papillomavirus.

Authors:  Matthias Wolf; Robert L Garcea; Nikolaus Grigorieff; Stephen C Harrison
Journal:  Proc Natl Acad Sci U S A       Date:  2010-03-22       Impact factor: 11.205

4.  Mechanism of eIF6-mediated inhibition of ribosomal subunit joining.

Authors:  Marco Gartmann; Michael Blau; Jean-Paul Armache; Thorsten Mielke; Maya Topf; Roland Beckmann
Journal:  J Biol Chem       Date:  2010-03-31       Impact factor: 5.157

5.  Atomic model of an infectious rotavirus particle.

Authors:  Ethan C Settembre; James Z Chen; Philip R Dormitzer; Nikolaus Grigorieff; Stephen C Harrison
Journal:  EMBO J       Date:  2010-12-14       Impact factor: 11.598

6.  Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions.

Authors:  Bertrand Beckert; Alexej Kedrov; Daniel Sohmen; Georg Kempf; Klemens Wild; Irmgard Sinning; Henning Stahlberg; Daniel N Wilson; Roland Beckmann
Journal:  Nat Struct Mol Biol       Date:  2015-09-07       Impact factor: 15.369

Review 7.  Single-particle cryo-electron microscopy of macromolecular complexes.

Authors:  Georgios Skiniotis; Daniel R Southworth
Journal:  Microscopy (Oxf)       Date:  2015-11-25       Impact factor: 1.571

8.  Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling.

Authors:  Clara Barrio-Garcia; Matthias Thoms; Dirk Flemming; Lukas Kater; Otto Berninghausen; Jochen Baßler; Roland Beckmann; Ed Hurt
Journal:  Nat Struct Mol Biol       Date:  2015-11-30       Impact factor: 15.369

9.  Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction.

Authors:  Xing Zhang; Ethan Settembre; Chen Xu; Philip R Dormitzer; Richard Bellamy; Stephen C Harrison; Nikolaus Grigorieff
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-31       Impact factor: 11.205

10.  Automatic cryo-EM particle selection for membrane proteins in spherical liposomes.

Authors:  Yunhui Liu; Fred J Sigworth
Journal:  J Struct Biol       Date:  2014-01-24       Impact factor: 2.867
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