Literature DB >> 16869663

A new entry to polycyclic indole skeletons via palladium-catalyzed intramolecular heteroannulation.

Jianxiu Liu1, Ming Shen, Yongda Zhang, Guisheng Li, Ahmad Khodabocus, Sonia Rodriguez, Bo Qu, Vittorio Farina, Chris H Senanayake, Bruce Z Lu.   

Abstract

[reaction: see text] A one-step method was developed for elaboration of a variety of polycyclic indole skeletons via a novel palladium-catalyzed intramolecular indolization of 2-chloroanilines bearing tethered acetylenes. This novel intramolecular indolization method unveils an unusual syn amidopalladation pathway of a tethered alkyne.

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Year:  2006        PMID： 16869663     DOI： 10.1021/ol061440j

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  A Pd(0)-mediated indole (macro)cyclization reaction.

Authors:  Steven P Breazzano; Yam B Poudel; Dale L Boger
Journal:  J Am Chem Soc       Date:  2013-01-17       Impact factor: 15.419

2.  A Mild and General Larock Indolization Protocol for the Preparation of Unnatural Tryptophans.

Authors:  Kangway V Chuang; Madeleine E Kieffer; Sarah E Reisman
Journal:  Org Lett       Date:  2016-09-06       Impact factor: 6.005

3.  Intramolecular hydroamination of alkynic sulfonamides catalyzed by a gold-triethynylphosphine complex: Construction of azepine frameworks by 7-exo-dig cyclization.

Authors:  Hideto Ito; Tomoya Harada; Hirohisa Ohmiya; Masaya Sawamura
Journal:  Beilstein J Org Chem       Date:  2011-07-08       Impact factor: 2.883

4.  Synthesis of substituted 2-aminoimidazoles via Pd-catalyzed alkyne carboamination reactions. Application to the synthesis of preclathridine natural products.

Authors:  Blane P Zavesky; Nicholas R Babij; John P Wolfe
Journal:  Org Lett       Date:  2014-09-08       Impact factor: 6.005
  4 in total

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