OBJECTIVES: To describe the incidence and prevalence of Clostridium difficile-associated diarrhea (CDAD) in a long-term care facility (LTCF). DESIGN: Retrospective review of CDAD cases between July 2001 and December 2003. SETTING: Two hundred two-bed LTCF affiliated with an academic medical center in Baltimore, Maryland. PARTICIPANTS: All residents of the facility during July 2001 to December 2003. MEASUREMENTS: Clinical and laboratory-confirmed cases of CDAD. RESULTS: Incidence of CDAD ranged from 0 to 2.62 cases per 1,000 resident days. The highest rates were observed in residents of subacute units, whereas incidence was much lower on traditional nursing home units. Prevalence of CDAD at admission was greater on units (subacute and rehabilitative) where the majority of patients were admitted from hospital settings than on those where the majority of patients were admitted from the community (nursing home units). Recurrent disease occurred in 21.7% of patients with CDAD. CONCLUSION: CDAD remains a problem in the long-term care setting, and importation from the acute care setting accounts for a large proportion of the C. difficile seen LTCFs. As the population continues to age, issues of disease and infection in long-term care are expected to increase. New prevention and control strategies are needed to control the spread of CDAD in LTCFs.
OBJECTIVES: To describe the incidence and prevalence of Clostridium difficile-associated diarrhea (CDAD) in a long-term care facility (LTCF). DESIGN: Retrospective review of CDAD cases between July 2001 and December 2003. SETTING: Two hundred two-bed LTCF affiliated with an academic medical center in Baltimore, Maryland. PARTICIPANTS: All residents of the facility during July 2001 to December 2003. MEASUREMENTS: Clinical and laboratory-confirmed cases of CDAD. RESULTS: Incidence of CDAD ranged from 0 to 2.62 cases per 1,000 resident days. The highest rates were observed in residents of subacute units, whereas incidence was much lower on traditional nursing home units. Prevalence of CDAD at admission was greater on units (subacute and rehabilitative) where the majority of patients were admitted from hospital settings than on those where the majority of patients were admitted from the community (nursing home units). Recurrent disease occurred in 21.7% of patients with CDAD. CONCLUSION:CDAD remains a problem in the long-term care setting, and importation from the acute care setting accounts for a large proportion of the C. difficile seen LTCFs. As the population continues to age, issues of disease and infection in long-term care are expected to increase. New prevention and control strategies are needed to control the spread of CDAD in LTCFs.
Authors: I Patel; M Wungjiranirun; T Theethira; J Villafuerte-Galvez; N Castillo; M Akbari; C D Alonso; D A Leffler; C P Kelly Journal: J Antimicrob Chemother Date: 2016-11-14 Impact factor: 5.790
Authors: Panayiotis D Ziakas; Nina Joyce; Ioannis M Zacharioudakis; Fainareti N Zervou; Richard W Besdine; Vincent Mor; Eleftherios Mylonakis Journal: Medicine (Baltimore) Date: 2016-08 Impact factor: 1.889
Authors: Eroboghene H Otete; Anand S Ahankari; Helen Jones; Kirsty J Bolton; Caroline W Jordan; Tim C Boswell; Mark H Wilcox; Neil M Ferguson; Charles R Beck; Richard L Puleston Journal: PLoS One Date: 2013-12-20 Impact factor: 3.240
Authors: Kamal Desai; Swati B Gupta; Erik R Dubberke; Vimalanand S Prabhu; Chantelle Browne; T Christopher Mast Journal: BMC Infect Dis Date: 2016-06-18 Impact factor: 3.090