Literature DB >> 16864150

Primary hypothyroidism presenting as ovarian tumor and precocious puberty in a prepubertal girl.

Adriana B Campaner1, Alessandro Scapinelli, Ruy O Machado, Roberto E Dos Santos, Geni W Beznos, Tsutomu Aoki.   

Abstract

We report a case of a prepubertal girl with juvenile primary hypothyroidism presenting as ovarian cysts and precocious puberty. The 7-year-old female was referred to our clinic because of a pelvic/abdominal mass and vaginal bleeding. Besides these findings, on physical examination we noticed the thyroid gland globally increased and the presence of secondary sexual characteristics. Based upon the clinical profile and investigations, the patient was diagnosed with juvenile primary hypothyroidism due to autoimmune thyroiditis. The cysts and precocious puberty resolved spontaneously after the simple replacement of thyroid hormone. It is important to bear in mind hypothyroidism in cases of girls presenting ovarian cysts and precocious puberty in order to avoid unnecessary surgery on the ovaries.

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Year:  2006        PMID: 16864150     DOI: 10.1080/09513590600819032

Source DB:  PubMed          Journal:  Gynecol Endocrinol        ISSN: 0951-3590            Impact factor:   2.260


  3 in total

1.  Ovarian tumors with elevated CA-125 levels and severe juvenile hypothyroidism: a need for increased awareness.

Authors:  Sriram Krishnamurthy; Anju Seth; Archana Puri; Rama Anand; Satinder Aneja
Journal:  Indian J Pediatr       Date:  2010-06-08       Impact factor: 1.967

2.  Acquired primary hypothyroidism: vaginal bleeding in a quiet child.

Authors:  Anne Wormsbecker; Cheril Clarson
Journal:  CMAJ       Date:  2010-02-22       Impact factor: 8.262

3.  Van Wyk and Grumbach syndrome revisited: imaging and clinical findings in pre- and postpubertal girls.

Authors:  Lorna P Browne; Hillary B Boswell; Eric J Crotty; Sara M O'Hara; Krista L Birkemeier; R Paul Guillerman
Journal:  Pediatr Radiol       Date:  2008-02-19
  3 in total

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