Literature DB >> 16861682

The yjeQ gene is required for virulence of Staphylococcus aureus.

Tracey L Campbell1, James Henderson, David E Heinrichs, Eric D Brown.   

Abstract

Gene products required for in vivo growth and survival of Staphylococcus aureus and other pathogens represent new targets for antimicrobial chemotherapy. In this study we created a Staphylococcus aureus yjeQ deletion strain and tested its virulence using a mouse kidney abscess infection model. The yjeQ deletion strain was compromised for growth in vitro and severely attenuated for virulence. We concluded that yjeQ is an attractive and novel new drug target.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16861682      PMCID： PMC1539590          DOI： 10.1128/IAI.00258-06

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  31 in total

1.  The role and regulation of the extracellular proteases of Staphylococcus aureus.

Authors:  Lindsey Shaw; Ewa Golonka; Jan Potempa; Simon J Foster
Journal:  Microbiology       Date:  2004-01       Impact factor: 2.777

2.  Studies of the interaction of Escherichia coli YjeQ with the ribosome in vitro.

Authors:  Denis M Daigle; Eric D Brown
Journal:  J Bacteriol       Date:  2004-03       Impact factor: 3.490

3.  The COG database: a tool for genome-scale analysis of protein functions and evolution.

Authors:  R L Tatusov; M Y Galperin; D A Natale; E V Koonin
Journal:  Nucleic Acids Res       Date:  2000-01-01       Impact factor: 16.971

Review 4.  Vancomycin-resistant Staphylococcus aureus: a new model of antibiotic resistance.

Authors:  K Hiramatsu
Journal:  Lancet Infect Dis       Date:  2001-10       Impact factor: 25.071

5.  Large-scale identification of genes required for full virulence of Staphylococcus aureus.

Authors:  Bret M Benton; J P Zhang; Skip Bond; Casey Pope; Todd Christian; Lawrence Lee; Kelly M Winterberg; Molly B Schmid; Jerry M Buysse
Journal:  J Bacteriol       Date:  2004-12       Impact factor: 3.490

6.  Role of siderophore biosynthesis in virulence of Staphylococcus aureus: identification and characterization of genes involved in production of a siderophore.

Authors:  Suzanne E Dale; Amanda Doherty-Kirby; Gilles Lajoie; David E Heinrichs
Journal:  Infect Immun       Date:  2004-01       Impact factor: 3.441

7.  YjeQ, an essential, conserved, uncharacterized protein from Escherichia coli, is an unusual GTPase with circularly permuted G-motifs and marked burst kinetics.

Authors:  Denis M Daigle; Laura Rossi; Albert M Berghuis; L Aravind; Eugene V Koonin; Eric D Brown
Journal:  Biochemistry       Date:  2002-09-17       Impact factor: 3.162

Review 8.  Staphylococcus aureus capsular polysaccharides.

Authors:  Katherine O'Riordan; Jean C Lee
Journal:  Clin Microbiol Rev       Date:  2004-01       Impact factor: 26.132

Review 9.  Vancomycin resistance in staphylococci.

Authors:  Arjun Srinivasan; James D Dick; Trish M Perl
Journal:  Clin Microbiol Rev       Date:  2002-07       Impact factor: 26.132

Review 10.  Understanding the mechanism of action of the exfoliative toxins of Staphylococcus aureus.

Authors:  Shamez Ladhani
Journal:  FEMS Immunol Med Microbiol       Date:  2003-11-28
View more
  15 in total

1.  Cryo-electron microscopy structure of the 30S subunit in complex with the YjeQ biogenesis factor.

Authors:  Ahmad Jomaa; Geordie Stewart; Jason A Mears; Inga Kireeva; Eric D Brown; Joaquin Ortega
Journal:  RNA       Date:  2011-09-29       Impact factor: 4.942

2.  RsgA releases RbfA from 30S ribosome during a late stage of ribosome biosynthesis.

Authors:  Simon Goto; Shingo Kato; Takatsugu Kimura; Akira Muto; Hyouta Himeno
Journal:  EMBO J       Date:  2010-11-23       Impact factor: 11.598

3.  Structural basis for the function of a small GTPase RsgA on the 30S ribosomal subunit maturation revealed by cryoelectron microscopy.

Authors:  Qiang Guo; Yi Yuan; Yanji Xu; Boya Feng; Liang Liu; Kai Chen; Ming Sun; Zhixiu Yang; Jianlin Lei; Ning Gao
Journal:  Proc Natl Acad Sci U S A       Date:  2011-07-25       Impact factor: 11.205

4.  Chemical inhibition of bacterial ribosome biogenesis shows efficacy in a worm infection model.

Authors:  Jonathan M Stokes; Carrie Selin; Silvia T Cardona; Eric D Brown
Journal:  Antimicrob Agents Chemother       Date:  2015-02-23       Impact factor: 5.191

5.  Escherichia coli rimM and yjeQ null strains accumulate immature 30S subunits of similar structure and protein complement.

Authors:  Vivian Leong; Meredith Kent; Ahmad Jomaa; Joaquin Ortega
Journal:  RNA       Date:  2013-04-23       Impact factor: 4.942

Review 6.  Genome-wide analysis of CCHC-type zinc finger (ZCCHC) proteins in yeast, Arabidopsis, and humans.

Authors:  Uri Aceituno-Valenzuela; Rosa Micol-Ponce; María Rosa Ponce
Journal:  Cell Mol Life Sci       Date:  2020-04-18       Impact factor: 9.261

7.  Isolation and characterization of biofilm formation-defective mutants of Staphylococcus aureus.

Authors:  Patrick H Tu Quoc; Pierre Genevaux; Maria Pajunen; Harri Savilahti; Costa Georgopoulos; Jacques Schrenzel; William L Kelley
Journal:  Infect Immun       Date:  2006-12-11       Impact factor: 3.441

8.  Genetic interaction screens with ordered overexpression and deletion clone sets implicate the Escherichia coli GTPase YjeQ in late ribosome biogenesis.

Authors:  Tracey L Campbell; Eric D Brown
Journal:  J Bacteriol       Date:  2008-01-25       Impact factor: 3.490

9.  Ribosome assembly defects subvert initiation Factor3 mediated scrutiny of bona fide start signal.

Authors:  Himanshu Sharma; B Anand
Journal:  Nucleic Acids Res       Date:  2019-12-02       Impact factor: 16.971

10.  ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-positive bacteria.

Authors:  Rebecca M Corrigan; Lauren E Bellows; Alison Wood; Angelika Gründling
Journal:  Proc Natl Acad Sci U S A       Date:  2016-03-07       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.