Literature DB >> 16858484

Patterns of illicit drug use and opioid abuse in patients with chronic pain at initial evaluation: a prospective, observational study.

Laxmaiah Manchikanti1, Kim S Damron, Carla D McManus, Renee C Barnhill.   

Abstract

BACKGROUND: Over the years, there has been a shift toward the increased reliance on opioids for the treatment of chronic pain. It is well known that some patients do not provide an appropriate history or underestimate their drug intake, and may exaggerate reported pain levels. Numerous studies have documented the incidence of illicit drug use and abuse of opioids in chronic pain patients. It is not known what proportion of patients have already been exposed to controlled substances prior to presenting for interventional pain management.
OBJECTIVE: To evaluate and identify the prevalence of controlled substance use, demographic characteristics, and psychological characteristics of patients presenting for interventional pain management along with illicit drug use. STUDY
DESIGN: A prospective, observational study.
METHODS: A total of 100 patients presenting at an interventional pain management setting for initial evaluation were evaluated by detailed history and urine drug testing for controlled substance use and illicit drug use.
RESULTS: Duration of pain on average was 9.3 years, 57% of the patients had involvement of more than one body region, 90% were taking opioids, 47% had been seen by 5 or more providers, and more than 70% presented with psychological problems. Twenty-three patients tested positive for illicit drugs and 12 patients were positive for opioids even though they had no prescription and denied taking opioids. Twenty-seven patients either under-reported (16) or over-reported (11) opioid use.
CONCLUSION: Ninety percent of these patients were taking opioids. Twenty-seven patients incorrectly reported opioid use, either underuse or overuse, with 23 patients using illicit drugs, 12 using non-prescription opioids, and with 35 of 100 patients at initial evaluation exhibiting one of the abuse behaviors.

Entities:  

Year:  2004        PMID: 16858484

Source DB:  PubMed          Journal:  Pain Physician        ISSN: 1533-3159            Impact factor:   4.965


  17 in total

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2.  Adherence to clinical guidelines for opioid therapy for chronic pain in patients with substance use disorder.

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Journal:  J Gen Intern Med       Date:  2011-05-12       Impact factor: 5.128

3.  Profiles of Urine Drug Test in Clinical Pain Patients vs Pain Research Study Subjects.

Authors:  Cheng-ting Lee; Trang T Vo; Abigail S Cohen; Shihab Ahmed; Yi Zhang; Jianren Mao; Lucy Chen
Journal:  Pain Med       Date:  2016-01-28       Impact factor: 3.750

Review 4.  Targeting Opioid-Induced Hyperalgesia in Clinical Treatment: Neurobiological Considerations.

Authors:  Caroline A Arout; Ellen Edens; Ismene L Petrakis; Mehmet Sofuoglu
Journal:  CNS Drugs       Date:  2015-06       Impact factor: 5.749

Review 5.  The Mesolimbic Dopamine System in Chronic Pain and Associated Affective Comorbidities.

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Journal:  Biol Psychiatry       Date:  2020-01-01       Impact factor: 13.382

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7.  Nonprescription use of pain relievers by middle-aged and elderly community-living adults: National Survey on Drug Use and Health.

Authors:  Dan G Blazer; Li-Tzy Wu
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8.  Positive airway pressure therapy in patients with opioid-related central sleep apnea.

Authors:  Anthony Troitino; Nawman Labedi; Thomas Kufel; Ali A El-Solh
Journal:  Sleep Breath       Date:  2013-09-24       Impact factor: 2.816

9.  Prescription opioid aberrant behaviors: a pilot study of sex differences.

Authors:  Sudie E Back; Rebecca A Payne; Angela E Waldrop; Arthur Smith; Scott Reeves; Kathleen T Brady
Journal:  Clin J Pain       Date:  2009 Jul-Aug       Impact factor: 3.442

10.  Under treatment of pain: a prescription for opioid misuse among the elderly?

Authors:  Maria A Levi-Minzi; Hilary L Surratt; Steven P Kurtz; Mance E Buttram
Journal:  Pain Med       Date:  2013-07-10       Impact factor: 3.750

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