Literature DB >> 16857222

Iridoid glycosides from Harpagophytum procumbens D.C. (devil's claw).

Jin Qi1, Ji-Jun Chen, Zhi-Hong Cheng, Jia-Hong Zhou, Bo-Yang Yu, Samuel X Qiu.   

Abstract

Iridoid glycosides, harprocumbide A (6''-O-alpha-D-galactopyranosylharpagoside, 1) and harprocumbide B (6''-O-(cis-p-coumaroyl)-procumbide, 2) were isolated from the tubers of Harpagophytum prucumbens D.C., along with nine known iridoid glycosides 6-O-alpha-D-galactopyranosylharpagoside (3), and harpagoside (4), harpagide (5), 8-cinnamoylmyoporoside (6), 8-O-feruloylhapagide (7), procumbide (8), 6''-O-(p-coumaroyl)-procumbide (9), 8-O-(p-coumaroyl)-harpagide (10) and 8-O-(cis-p-coumaroyl)-harpagide (11). Compound 10 showed marginal inhibition activity against macrophages respiratory burst.

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Year:  2006        PMID: 16857222     DOI: 10.1016/j.phytochem.2006.05.029

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  6 in total

1.  Current nutraceuticals in the management of osteoarthritis: a review.

Authors:  Nahid Akhtar; Tariq M Haqqi
Journal:  Ther Adv Musculoskelet Dis       Date:  2012-06       Impact factor: 5.346

2.  Devil's Claw to suppress appetite--ghrelin receptor modulation potential of a Harpagophytum procumbens root extract.

Authors:  Cristina Torres-Fuentes; Wessel F Theeuwes; Michael K McMullen; Anna K McMullen; Timothy G Dinan; John F Cryan; Harriët Schellekens
Journal:  PLoS One       Date:  2014-07-28       Impact factor: 3.240

3.  Devil's claw (Harpagophytum procumbens) ameliorates the neurobehavioral changes and neurotoxicity in female rats exposed to arsenic.

Authors:  Rupasree Peruru; R Usha Rani; Jhansyrani Thatiparthi; Sunitha Sampathi; Sujatha Dodoala; K V S R G Prasad
Journal:  Heliyon       Date:  2020-05-08

4.  Harpagoside attenuates local bone Erosion and systemic osteoporosis in collagen-induced arthritis in mice.

Authors:  Ju-Young Kim; Yoon-Hee Cheon; Sung-Jun Ahn; Sung Chul Kwak; Chong Hyuk Chung; Chang Hoon Lee; Myeung Su Lee
Journal:  BMC Complement Med Ther       Date:  2022-08-10

Review 5.  The Nutraceuticals as Modern Key to Achieve Erythrocyte Oxidative Stress Fighting in Osteoarthritis.

Authors:  Alessia Mariano; Irene Bigioni; Francesco Misiti; Luigi Fattorini; Anna Scotto d'Abusco; Angelo Rodio
Journal:  Curr Issues Mol Biol       Date:  2022-08-05       Impact factor: 2.976

6.  Alteration of Neutrophil Reactive Oxygen Species Production by Extracts of Devil's Claw (Harpagophytum).

Authors:  Mbaki Muzila; Kimmo Rumpunen; Helen Wright; Helen Roberts; Melissa Grant; Hilde Nybom; Jasna Sehic; Anders Ekholm; Cecilia Widén
Journal:  Oxid Med Cell Longev       Date:  2016-06-27       Impact factor: 6.543

  6 in total

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