| Literature DB >> 1685049 |
R J Yáñez1, A Moya, E Viñuela, E Domingo.
Abstract
Repetitive nucleotide sequencing of a dispensable genomic segment of a clonal population of African swine fever (ASF) virus has been carried out to estimate the mutant frequency to neutral alleles. Since no mutations have been detected in a total of 54026 nucleotides screened, the maximum mutant frequency is 5.5 x 10(-5) substitutions/nucleotide (95% confidence level). The result renders very unlikely the occurrence of hypermutational events during ASF virus DNA replication, at least within the selected DNA fragment.Entities:
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Year: 1991 PMID: 1685049 DOI: 10.1016/0168-1702(91)90080-f
Source DB: PubMed Journal: Virus Res ISSN: 0168-1702 Impact factor: 3.303