Literature DB >> 1684521

Breast biopsy nuclear pellets are a convenient source of DNA for routine determination of Her-2/neu gene amplification.

O Malka1, Y Pollack, D Benharroch, Y Cohen, R Levy, I Yanai-Inbar, J Gopas.   

Abstract

Cell nuclei from breast biopsies are a byproduct of routine hormone receptor determination and are usually discarded. We report here that DNA purified from this source is suitable for use in conventional Southern blot or Polymerase Chain Reaction (PCR) techniques to screen for Her-2/neu amplification, enabling efficient use of limited biopsy material.

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Year:  1991        PMID: 1684521     DOI: 10.1007/bf01975205

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN: 0167-6806            Impact factor:   4.872


  19 in total

1.  Proto-oncogene amplification and human breast tumor phenotype.

Authors:  J Adnane; P Gaudray; M P Simon; J Simony-Lafontaine; P Jeanteur; C Theillet
Journal:  Oncogene       Date:  1989-11       Impact factor: 9.867

2.  In vitro expression of human p53 cDNA clones and characterization of the cloned human p53 gene.

Authors:  D Wolf; Z Laver-Rudich; V Rotter
Journal:  Mol Cell Biol       Date:  1985-08       Impact factor: 4.272

3.  Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription.

Authors:  M S Schlissel; D Baltimore
Journal:  Cell       Date:  1989-09-08       Impact factor: 41.582

4.  Sporadic amplification of the HER2/neu protooncogene in adenocarcinomas of various tissues.

Authors:  M Tal; M Wetzler; Z Josefberg; A Deutch; M Gutman; D Assaf; R Kris; Y Shiloh; D Givol; J Schlessinger
Journal:  Cancer Res       Date:  1988-03-15       Impact factor: 12.701

5.  Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer.

Authors:  D J Slamon; W Godolphin; L A Jones; J A Holt; S G Wong; D E Keith; W J Levin; S G Stuart; J Udove; A Ullrich
Journal:  Science       Date:  1989-05-12       Impact factor: 47.728

6.  Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor.

Authors:  T Yamamoto; S Ikawa; T Akiyama; K Semba; N Nomura; N Miyajima; T Saito; K Toyoshima
Journal:  Nature       Date:  1986 Jan 16-22       Impact factor: 49.962

7.  Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene.

Authors:  D J Slamon; G M Clark; S G Wong; W J Levin; A Ullrich; W L McGuire
Journal:  Science       Date:  1987-01-09       Impact factor: 47.728

8.  Proto-oncogene abnormalities in human breast cancer: correlations with anatomic features and clinical course of disease.

Authors:  M J Cline; H Battifora; J Yokota
Journal:  J Clin Oncol       Date:  1987-07       Impact factor: 44.544

9.  The neu oncogene: an erb-B-related gene encoding a 185,000-Mr tumour antigen.

Authors:  A L Schechter; D F Stern; L Vaidyanathan; S J Decker; J A Drebin; M I Greene; R A Weinberg
Journal:  Nature       Date:  1984 Dec 6-12       Impact factor: 49.962

10.  Correlation of c-erbB-2 gene amplification and protein expression in human breast carcinoma with nodal status and nuclear grading.

Authors:  M S Berger; G W Locher; S Saurer; W J Gullick; M D Waterfield; B Groner; N E Hynes
Journal:  Cancer Res       Date:  1988-03-01       Impact factor: 12.701

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