Literature DB >> 16844371

Structure of a new cyclic nonapeptide, segetalin F, and vasorelaxant activity of segetalins from Vaccaria segetalis.

Hiroshi Morita1, Michiko Eda, Toru Iizuka, Yusuke Hirasawa, Mitsuhiro Sekiguchi, Young Sook Yun, Hideji Itokawa, Koichi Takeya.   

Abstract

A new cyclic nonapeptide, segetalin F, has been isolated from the seeds of Vaccaria segetalis and the structure including absolute stereochemistry was elucidated by using 2D NMR and chemical means. A series of segetalins showed a vasorelaxant activity against norepinephrine (NE)-induced contractions of rat aorta.

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Year:  2006        PMID: 16844371     DOI: 10.1016/j.bmcl.2006.06.083

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  13 in total

1.  Vasorelaxant effect of FR900359 from Ardisia crenata on rat aortic artery.

Authors:  Kazumasa Zaima; Jun Deguchi; Yosuke Matsuno; Toshio Kaneda; Yusuke Hirasawa; Hiroshi Morita
Journal:  J Nat Med       Date:  2012-03-03       Impact factor: 2.343

2.  Studies on the constituents from the fruits of Phaleria macrocarpa.

Authors:  Shiori Oshimi; Kazumasa Zaima; Yosuke Matsuno; Yusuke Hirasawa; Toru Iizuka; Herra Studiawan; Gunawan Indrayanto; Noor Cholies Zaini; Hiroshi Morita
Journal:  J Nat Med       Date:  2007-11-03       Impact factor: 2.343

3.  Characterization of the macrocyclase involved in the biosynthesis of RiPP cyclic peptides in plants.

Authors:  Jonathan R Chekan; Paola Estrada; Patrick S Covello; Satish K Nair
Journal:  Proc Natl Acad Sci U S A       Date:  2017-06-05       Impact factor: 11.205

4.  Vasorelaxant effect of isoquinoline derivatives from two species of Popowia perakensis and Phaeanthus crassipetalus on rat aortic artery.

Authors:  Kazumasa Zaima; Yuka Takeyama; Ikumi Koga; Aiko Saito; Haruka Tamamoto; Saripah Salbiah Syed Abd Azziz; Mat Ropi Mukhtar; Khalijah Awang; A Hamid A Hadi; Hiroshi Morita
Journal:  J Nat Med       Date:  2011-10-28       Impact factor: 2.343

5.  Vasorelaxant activity of indole alkaloids from Tabernaemontana dichotoma.

Authors:  Kazumasa Zaima; Ikumi Koga; Nobuhide Iwasawa; Takahiro Hosoya; Yusuke Hirasawa; Toshio Kaneda; Intan Safinar Ismail; Nordin Hj Lajis; Hiroshi Morita
Journal:  J Nat Med       Date:  2012-02-21       Impact factor: 2.343

6.  Applying Promiscuous RiPP Enzymes to Peptide Backbone N-Methylation Chemistry.

Authors:  Snigdha Sarkar; Wenjia Gu; Eric W Schmidt
Journal:  ACS Chem Biol       Date:  2022-07-12       Impact factor: 4.634

Review 7.  Biosynthetic Proteases That Catalyze the Macrocyclization of Ribosomally Synthesized Linear Peptides.

Authors:  Chayanid Ongpipattanakul; Satish K Nair
Journal:  Biochemistry       Date:  2018-03-27       Impact factor: 3.162

8.  The two-step biosynthesis of cyclic peptides from linear precursors in a member of the plant family Caryophyllaceae involves cyclization by a serine protease-like enzyme.

Authors:  Carla J S Barber; Pareshkumar T Pujara; Darwin W Reed; Shiela Chiwocha; Haixia Zhang; Patrick S Covello
Journal:  J Biol Chem       Date:  2013-03-13       Impact factor: 5.157

9.  Alkaloids from the seeds of Peganum harmala showing antiplasmodial and vasorelaxant activities.

Authors:  Adil Astulla; Kazumasa Zaima; Yosuke Matsuno; Yusuke Hirasawa; Wiwied Ekasari; Aty Widyawaruyanti; Noor Cholies Zaini; Hiroshi Morita
Journal:  J Nat Med       Date:  2008-06-04       Impact factor: 2.343

10.  Spontaneous head-to-tail cyclization of unprotected linear peptides with the KAHA ligation.

Authors:  Florian Rohrbacher; Gildas Deniau; Anatol Luther; Jeffrey W Bode
Journal:  Chem Sci       Date:  2015-06-10       Impact factor: 9.825

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