Literature DB >> 16841250

Electrochemical biosensor evaluation of the interaction between DNA and metallo-drugs.

Marco Mascini1, Graziana Bagni, Maria Letizia Di Pietro, Mauro Ravera, Sara Baracco, Domenico Osella.   

Abstract

Electrochemical techniques were used to study the interaction between a panel of antiproliferative metallo-drugs and double-stranded DNA immobilized on screen-printed electrodes as a model of the analogous interaction occurring in solution. The propensity of a given metal drug to interact with DNA was measured as a function of the decrease of guanine oxidation signal, which was detected by square wave voltammetry. Estimates of variations in experimental parameters, such as the concentration of complexes, time following dissolution (ageing time) and the presence of chloride, are provided.

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Year:  2006        PMID： 16841250     DOI： 10.1007/s10534-005-4340-3

Source DB:  PubMed          Journal:  Biometals        ISSN： 0966-0844            Impact factor:   2.949


  9 in total

1.  Titanocene-phosphine derivatives as precursors to cytotoxic heterometallic TiAu2 and TiM (M = Pd, Pt) compounds. Studies of their interactions with DNA.

Authors:  Jose F González-Pantoja; Michael Stern; Andrzej A Jarzecki; Eva Royo; Elisa Robles-Escajeda; Armando Varela-Ramírez; Renato J Aguilera; María Contel
Journal:  Inorg Chem       Date:  2011-09-29       Impact factor: 5.165

2.  Silver(I) metallodrugs of thiosemicarbazones and naproxen: biocompatibility, in vitro anti-proliferative activity and in silico interaction studies with EGFR, VEGFR2 and LOX receptors.

Authors:  Sundaram Bharathi; Dharmasivam Mahendiran; Raju Senthil Kumar; Hyo Jeong Choi; Mani Gajendiran; Kyobum Kim; Aziz Kalilur Rahiman
Journal:  Toxicol Res (Camb)       Date:  2020-03-11       Impact factor: 3.524

3.  Hexanuclear self-assembled arene-ruthenium nano-prismatic cages: potential anticancer agents.

Authors:  Vaishali Vajpayee; Yoon Jung Yang; Se Chan Kang; Hyunuk Kim; In Su Kim; Ming Wang; Peter J Stang; Ki-Whan Chi
Journal:  Chem Commun (Camb)       Date:  2011-03-30       Impact factor: 6.222

4.  DNA electrochemical biosensor for metallic drugs at physiological conditions.

Authors:  Angel J Santiago-Lopez; José L Vera; Enrique Meléndez
Journal:  J Electroanal Chem (Lausanne)       Date:  2014-10-01       Impact factor: 4.464

5.  SOD mimetic activity and antiproliferative properties of a novel tetra nuclear copper (II) complex.

Authors:  Sagiv Weintraub; Yoni Moskovitz; Ohad Fleker; Ariel R Levy; Aviv Meir; Sharon Ruthstein; Laurent Benisvy; Arie Gruzman
Journal:  J Biol Inorg Chem       Date:  2015-11-07       Impact factor: 3.358

6.  Synthesis and antimicrobial activity of novel Ag-N-hetero-cyclic carbene complexes.

Authors:  Ilknur Ozdemir; Emine Ozge Ozcan; Selami Günal; Nevin Gürbüz
Journal:  Molecules       Date:  2010-04-08       Impact factor: 4.411

7.  Combined computational and experimental studies on cysteine-sulfadiazine adduct formation.

Authors:  Nursel Acar SelÇukİ; Emine CoŞkun; Ender BİÇer
Journal:  Turk J Chem       Date:  2020-04-01       Impact factor: 1.239

8.  DNA-metallodrugs interactions signaled by electrochemical biosensors: an overview.

Authors:  Mauro Ravera; Graziana Bagni; Marco Mascini; Domenico Osella
Journal:  Bioinorg Chem Appl       Date:  2007       Impact factor: 7.778

Review 9.  An Overview of Label-free Electrochemical Protein Sensors.

Authors:  Mun 'delanji Vestergaard; Kagan Kerman; Eiichi Tamiya
Journal:  Sensors (Basel)       Date:  2007-12-20       Impact factor: 3.576
  9 in total

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