BACKGROUND: Reports during the early 1990s indicated non-Hodgkin's lymphoma (NHL) as one of the most rapidly increasing malignancies. More recent trends remain poorly characterized, as do the underlying reasons for NHL time trends, in particular, the effect of changes in classification and registration of lymphoproliferative malignancies. Insights into the descriptive epidemiology of NHL may shed light upon its elusive etiology. METHODS: We used data from the Swedish, Danish, and Finnish national cancer registers to assess the incidences of NHL and other lymphoproliferative malignancies between 1960 and 2004. Using Poisson regression, we estimated the annual rate of change in NHL incidence per decade by sex, age, and country. RESULTS: In Sweden, Denmark, and Finland, the NHL incidence increased in both genders and all age categories by about 4% every year up until the early 1990s. Thereafter, the incidence increased at a slower rate (ages 60-79 years), stabilized (ages 50-59 and > or =80 years), and decreased (ages 0-49 years), respectively, similarly for males and females in the three countries. Time trends of NHL were not reciprocated and explained by trends for other lymphoproliferative malignancies nor explained by trends in NHL as secondary primaries or NHL diagnosed postmortem. CONCLUSIONS: The epidemic increase of NHL has recently subsided. Changes in the classification of lymphoproliferative malignancies, or occurrence of NHL as second primaries, only offer a marginal explanation.
BACKGROUND: Reports during the early 1990s indicated non-Hodgkin's lymphoma (NHL) as one of the most rapidly increasing malignancies. More recent trends remain poorly characterized, as do the underlying reasons for NHL time trends, in particular, the effect of changes in classification and registration of lymphoproliferative malignancies. Insights into the descriptive epidemiology of NHL may shed light upon its elusive etiology. METHODS: We used data from the Swedish, Danish, and Finnish national cancer registers to assess the incidences of NHL and other lymphoproliferative malignancies between 1960 and 2004. Using Poisson regression, we estimated the annual rate of change in NHL incidence per decade by sex, age, and country. RESULTS: In Sweden, Denmark, and Finland, the NHL incidence increased in both genders and all age categories by about 4% every year up until the early 1990s. Thereafter, the incidence increased at a slower rate (ages 60-79 years), stabilized (ages 50-59 and > or =80 years), and decreased (ages 0-49 years), respectively, similarly for males and females in the three countries. Time trends of NHL were not reciprocated and explained by trends for other lymphoproliferative malignancies nor explained by trends in NHL as secondary primaries or NHL diagnosed postmortem. CONCLUSIONS: The epidemic increase of NHL has recently subsided. Changes in the classification of lymphoproliferative malignancies, or occurrence of NHL as second primaries, only offer a marginal explanation.
Authors: Frank Heinzelmann; Wolfgang Bethge; Dietrich Wilhelm Beelen; Matthias Stelljes; Peter Dreger; Marianne Engelhard; Jürgen Finke; Nikolaus Kröger; Ernst Holler; Martin Bornhäuser; Annerose Müller; Imme Haubitz; Hellmut Ottinger Journal: J Cancer Res Clin Oncol Date: 2018-04-05 Impact factor: 4.553
Authors: Meredith S Shiels; Eric A Engels; Martha S Linet; Christina A Clarke; Jianmin Li; H Irene Hall; Patricia Hartge; Lindsay M Morton Journal: Cancer Epidemiol Biomarkers Prev Date: 2013-04-17 Impact factor: 4.254
Authors: Lindsay M Morton; Joshua N Sampson; James R Cerhan; Jennifer J Turner; Claire M Vajdic; Sophia S Wang; Karin E Smedby; Silvia de Sanjosé; Alain Monnereau; Yolanda Benavente; Paige M Bracci; Brian C H Chiu; Christine F Skibola; Yawei Zhang; Sam M Mbulaiteye; Michael Spriggs; Dennis Robinson; Aaron D Norman; Eleanor V Kane; John J Spinelli; Jennifer L Kelly; Carlo La Vecchia; Luigino Dal Maso; Marc Maynadié; Marshall E Kadin; Pierluigi Cocco; Adele Seniori Costantini; Christina A Clarke; Eve Roman; Lucia Miligi; Joanne S Colt; Sonja I Berndt; Andrea Mannetje; Anneclaire J de Roos; Anne Kricker; Alexandra Nieters; Silvia Franceschi; Mads Melbye; Paolo Boffetta; Jacqueline Clavel; Martha S Linet; Dennis D Weisenburger; Susan L Slager Journal: J Natl Cancer Inst Monogr Date: 2014-08
Authors: James R Cerhan; Eric A Engels; Wendy Cozen; Scott Davis; Richard K Severson; Lindsay M Morton; Gloria Gridley; Patricia Hartge; Martha Linet Journal: Int J Cancer Date: 2008-08-15 Impact factor: 7.396
Authors: A Olayiwola Oluwasola; John A Olaniyi; Jesse A Otegbayo; Gabriel O Ogun; Titi S Akingbola; Cornelius O Ukah; Effiong E U Akang; Yetunde A Aken'Ova Journal: J Health Popul Nutr Date: 2011-08 Impact factor: 2.000