Literature DB >> 16833244

Artificial disc technology.

Q B Bao1, H A Yuan.   

Abstract

After approximately 40 years of research and development, artificial disc technology may finally be coming of age. A number of devices are either at the late stage of preclinical study or in the early stage of clinical trial, and the results are promising so far. Due to the multicomponent structure of the disc, surgeons performing disc arthroplasty have the option of replacing either the entire disc or a portion of it. The decision will be largely dependent on the pathological entity addressed, the condition of the patient's spinal disc and surrounding tissues, and the cost and potential risk of the procedure. Driven by demand, almost all the emphasis in artificial disc development has been placed on the lumbar disc, with a smaller effort directed toward the cervical disc. No attempt has been made to develop an artificial thoracic disc. However, by examining the differences and similarities in structure, anatomy, function, mechanism of degeneration, pathology, surgical technique, and complications between the lumbar and thoracic disc, the authors believe it is feasible to apply artificial disc technology in the treatment of thoracic disc disease. Nonetheless, due to the rarity of thoracic disc disease and the more stable structure of this spinal component, the demand for artificial disc or artificial nucleus technology for the thoracic disc probably will be smaller than that for lumbar disc technology.

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Year:  2000        PMID: 16833244     DOI: 10.3171/foc.2000.9.4.14

Source DB:  PubMed          Journal:  Neurosurg Focus        ISSN: 1092-0684            Impact factor:   4.047


  5 in total

1.  Anterior lumbar discectomy and disc replacement.

Authors:  Dick Zeilstra; Wolter Oosterhuis
Journal:  Eur Spine J       Date:  2011-06       Impact factor: 3.134

Review 2.  Strategies towards injectable, load-bearing materials for the intervertebral disc: a review and outlook.

Authors:  Cecilia Persson; Svante Berg
Journal:  J Mater Sci Mater Med       Date:  2012-09-29       Impact factor: 3.896

3.  Clinical study to evaluate the safety and effectiveness of the Aesculap Activ-L artificial disc in the treatment of degenerative disc disease.

Authors:  James J Yue; Fred F Mo
Journal:  BMC Surg       Date:  2010-04-09       Impact factor: 2.102

4.  We Need to Talk about Lumbar Total Disc Replacement.

Authors:  Stephen Beatty
Journal:  Int J Spine Surg       Date:  2018-08-03

Review 5.  Advances of Naturally Derived and Synthetic Hydrogels for Intervertebral Disk Regeneration.

Authors:  Guoke Tang; Bingyan Zhou; Feng Li; Weiheng Wang; Yi Liu; Xing Wang; Chao Liu; Xiaojian Ye
Journal:  Front Bioeng Biotechnol       Date:  2020-06-30
  5 in total

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