Literature DB >> 1683252

The effects of astemizole, cetirizine and loratadine on the time course of weal and flare reactions to histamine, codeine and antigen.

F Humphreys1, J A Hunter.   

Abstract

An open cross-over study was performed to assess the effects of astemizole, cetirizine and loratadine on weal and flare reactions to intradermal histamine, codeine and house dust mite antigen. Percentage inhibition of weal area, flare area and weal volume was greatest for cetirizine, then astemizole and smallest for loratadine. Wealing due to mast-cell degranulation with either codeine or antigen was less inhibited by all three antihistamines than that due to histamine itself. Time-course studies revealed similarities between wealing provoked by codeine and histamine but different characteristics to that induced by antigen.

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Year:  1991        PMID： 1683252     DOI： 10.1111/j.1365-2133.1991.tb14173.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN： 0007-0963            Impact factor:   9.302


  8 in total

Review 1.  Astemizole. A nonsedating antihistamine with fast and sustained activity.

Authors:  M M Janssens
Journal:  Clin Rev Allergy       Date:  1993

Review 2.  Clinical pharmacology of new histamine H1 receptor antagonists.

Authors:  F E Simons; K J Simons
Journal:  Clin Pharmacokinet       Date:  1999-05       Impact factor: 6.447

Review 3.  Cetirizine/pseudoephedrine.

Authors:  K Wellington; B Jarvis
Journal:  Drugs       Date:  2001       Impact factor: 9.546

4.  Cetirizine: a review of its use in allergic disorders.

Authors:  Monique P Curran; Lesley J Scott; Caroline M Perry
Journal:  Drugs       Date:  2004       Impact factor: 9.546

Review 5.  Urticaria. Recognition, causes and treatment.

Authors:  A D Ormerod
Journal:  Drugs       Date:  1994-11       Impact factor: 9.546

6.  Predicting and establishing the clinical efficacy of a histamine h(1)-receptor antagonist : desloratadine, the model paradigm.

Authors:  Glenis Scadding
Journal:  Clin Drug Investig       Date:  2005       Impact factor: 2.859

Review 7.  Loratadine. A reappraisal of its pharmacological properties and therapeutic use in allergic disorders.

Authors:  M Haria; A Fitton; D H Peters
Journal:  Drugs       Date:  1994-10       Impact factor: 9.546

8.  MRGPRX2 Is the Codeine Receptor of Human Skin Mast Cells: Desensitization through β-Arrestin and Lack of Correlation with the FcεRI Pathway.

Authors:  Magda Babina; Zhao Wang; Saptarshi Roy; Sven Guhl; Kristin Franke; Metin Artuc; Hydar Ali; Torsten Zuberbier
Journal:  J Invest Dermatol       Date:  2020-10-13       Impact factor: 8.551
  8 in total

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