Literature DB >> 16821762

5-Hydroxytryptamine 2C (5-HT2C) receptor agonists as potential antiobesity agents.

Björn M Nilsson1.   

Abstract

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Year:  2006        PMID： 16821762     DOI： 10.1021/jm058240i

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  16 in total

1.  HTS and rational drug design to generate a class of 5-HT(2C)-selective ligands for possible use in schizophrenia.

Authors:  Alan P Kozikowski; Sung Jin Cho; Niels H Jensen; John A Allen; Andreas M Svennebring; Bryan L Roth
Journal:  ChemMedChem       Date:  2010-08-02       Impact factor: 3.466

2.  Selective serotonin receptor stimulation of the medial nucleus accumbens differentially affects appetitive motivation for food on a progressive ratio schedule of reinforcement.

Authors:  Wayne E Pratt; Megan A Schall; Eugene Choi
Journal:  Neurosci Lett       Date:  2012-01-24       Impact factor: 3.046

3.  Rational Drug Design Leading to the Identification of a Potent 5-HT(2C) Agonist Lacking 5-HT(2B) Activity.

Authors:  Gang Chen; Sung Jin Cho; Xi-Ping Huang; Niels H Jensen; Andreas Svennebring; Maria F Sassano; Bryan L Roth; Alan P Kozikowski
Journal:  ACS Med Chem Lett       Date:  2011-10-10       Impact factor: 4.345

4.  A systematic investigation of the differential roles for ventral tegmentum serotonin 1- and 2-type receptors on food intake in the rat.

Authors:  Wayne E Pratt; Kara A Clissold; Peagan Lin; Amanda E Cain; Alexa F Ciesinski; Thomas R Hopkins; Adeolu O Ilesanmi; Erin A Kelly; Zachary Pierce-Messick; Daniel S Powell; Ian A Rosner
Journal:  Brain Res       Date:  2016-07-16       Impact factor: 3.252

5.  Risperidone-induced weight gain in referred children with autism spectrum disorders is associated with a common polymorphism in the 5-hydroxytryptamine 2C receptor gene.

Authors:  Pieter J Hoekstra; Pieter W Troost; Bertine E Lahuis; Hans Mulder; Erik J Mulder; Barbara Franke; Jan K Buitelaar; George M Anderson; Lawrence Scahill; Ruud B Minderaa
Journal:  J Child Adolesc Psychopharmacol       Date:  2010-12       Impact factor: 2.576

6.  The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control.

Authors:  Guy A Higgins; Leo B Silenieks; Anne Rossmann; Zoe Rizos; Kevin Noble; Ashlie D Soko; Paul J Fletcher
Journal:  Neuropsychopharmacology       Date:  2011-12-21       Impact factor: 7.853

7.  Regioselective alkylation of 1,3,4,5-tetrahydrobenzo[d]azepin-2-one and biological evaluation of the resulting alkylated products as potentially selective 5-HT₂c agonists.

Authors:  Navnit Prajapati; Rajani Giridhar; Anshuman Sinha; Ashish M Kanhed; Mange Ram Yadav
Journal:  Mol Divers       Date:  2015-04-28       Impact factor: 2.943

8.  Selective 5-hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: identification of drugs with antidepressant-like action.

Authors:  Sung Jin Cho; Niels H Jensen; Toru Kurome; Sudhakar Kadari; Michael L Manzano; Jessica E Malberg; Barbara Caldarone; Bryan L Roth; Alan P Kozikowski
Journal:  J Med Chem       Date:  2009-04-09       Impact factor: 7.446

9.  Effect of (-)-trans-PAT, a novel 5-HT2C receptor agonist, on intake of palatable food in mice.

Authors:  Neil E Rowland; Erica M Crump; Nancy Nguyen; Kimberly Robertson; Zhuming Sun; Raymond G Booth
Journal:  Pharmacol Biochem Behav       Date:  2008-07-19       Impact factor: 3.533

Review 10.  Dual dopamine/serotonin releasers: potential treatment agents for stimulant addiction.

Authors:  Richard B Rothman; Bruce E Blough; Michael H Baumann
Journal:  Exp Clin Psychopharmacol       Date:  2008-12       Impact factor: 3.157
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