Literature DB >> 16820648

Flexible versus nonflexible mitral valve rings for congestive heart failure: differential durability of repair.

Martinus T Spoor1, Amy Geltz, Steven F Bolling.   

Abstract

BACKGROUND: Surgical intervention is playing an increasingly important therapeutic role in congestive heart failure (CHF) patients with ischemia and dilated cardiomyopathy. Their mitral regurgitation (MR) is a result of left ventricular (LV) geometrical distortion. The optimal type of ring for CHF patients with geometric ventricular-based MR is unknown. This study reviewed the results of flexible versus nonflexible complete mitral valve rings in CHF patients with geometric mitral regurgitation. METHODS AND
RESULTS: Using a prospectively maintained database, patients undergoing mitral valve reconstruction (MVR) with either a flexible or nonflexible complete ring were identified on the basis of preoperative ejection fraction (EF) < or = 30% and no primary mitral pathology. These 2 groups of CHF patients with severe geometric MR were then compared in terms of recurrent MR requiring reoperation. Between 1992 and 2004, 289 patients with EF < or = 30%, received an undersized complete mitral annuloplasty ring as their MVR procedure. Of these, 170 patients had a flexible complete ring. In follow-up, 16 "flexible" patients (9.4%) required a repeat procedure for significant recurrent geometric MR and CHF (10 replacements, 3 re-repairs, 3 transplants). The average time to reoperation was 2.4 years. In contrast, 119 patients with an EF < or = 30% received a MVR using an undersized nonflexible complete ring. Only 3 "non-flexible" patients required a repeat operation, MVR (1), and 2 patients required a transplant. The time to reoperation was 4.0 years. A significant difference in reoperation rates, for recurrent MR, between the 2 groups (P=0.012). There were no differences between groups, in terms of age, ring size used, preoperative EF, LV size, MR grade, or New York Heart Association class.
CONCLUSIONS: Patients with CHF having a flexible ring have a higher likelihood of developing recurrent MR requiring reoperation. The use of a nonflexible ring appears to significantly reduce the need for repeat surgical procedures. Further refinement and development of nonflexible ring systems, aimed at LV restoration, deserve ongoing investigation.

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Year:  2006        PMID: 16820648     DOI: 10.1161/CIRCULATIONAHA.105.001453

Source DB:  PubMed          Journal:  Circulation        ISSN: 0009-7322            Impact factor:   29.690


  18 in total

Review 1.  Surgical approach to mitral regurgitation in chronic heart failure: when is it an option?

Authors:  Juan A Crestanello
Journal:  Curr Heart Fail Rep       Date:  2012-03

Review 2.  Devices for mitral valve repair.

Authors:  Paolo Denti; Francesco Maisano; Ottavio Alfieri
Journal:  J Cardiovasc Transl Res       Date:  2014-01-23       Impact factor: 4.132

3.  In-vivo analysis of selectively flexible mitral annuloplasty rings using three-dimensional echocardiography.

Authors:  Khurram Owais; Han Kim; Kamal R Khabbaz; Remco Bergman; Robina Matyal; Robert C Gorman; Joseph H Gorman; Philip E Hess; Feroze Mahmood
Journal:  Ann Thorac Surg       Date:  2014-03-06       Impact factor: 4.330

Review 4.  Treatment and management of mitral regurgitation.

Authors:  Michele De Bonis; Francesco Maisano; Giovanni La Canna; Ottavio Alfieri
Journal:  Nat Rev Cardiol       Date:  2011-11-22       Impact factor: 32.419

Review 5.  Surgical ventricular restoration for the treatment of heart failure.

Authors:  Gerald Buckberg; Constantine Athanasuleas; John Conte
Journal:  Nat Rev Cardiol       Date:  2012-11-13       Impact factor: 32.419

Review 6.  Surgical Treatment of Ischemic Mitral Regurgitation: Valve Repair Versus Replacement.

Authors:  Abhishek Sharma; Sahil Agrawal; Sunny Goel; Jeffrey S Borer
Journal:  Curr Cardiol Rep       Date:  2017-01       Impact factor: 2.931

7.  Mitral cerclage annuloplasty, a novel transcatheter treatment for secondary mitral valve regurgitation: initial results in swine.

Authors:  June-Hong Kim; Ozgur Kocaturk; Cengizhan Ozturk; Anthony Z Faranesh; Merdim Sonmez; Smita Sampath; Christina E Saikus; Ann H Kim; Venkatesh K Raman; J Andrew Derbyshire; William H Schenke; Victor J Wright; Colin Berry; Elliot R McVeigh; Robert J Lederman
Journal:  J Am Coll Cardiol       Date:  2009-08-11       Impact factor: 24.094

Review 8.  Computational mitral valve evaluation and potential clinical applications.

Authors:  Krishnan B Chandran; Hyunggun Kim
Journal:  Ann Biomed Eng       Date:  2014-08-19       Impact factor: 3.934

9.  [Mitral regurgitation in heart failure. Surgical therapy].

Authors:  H Aubin; H Kamiya; A Lichtenberg
Journal:  Herz       Date:  2013-03       Impact factor: 1.443

Review 10.  Functional mitral regurgitation: a 30-year unresolved surgical journey from valve replacement to complex valve repairs.

Authors:  Francesco Onorati; Francesco Santini; Rajesh Dandale; Andrea Rossi; Esther Campopiano; Konstantinos Pechlivanidis; Daniele Calzaferri; Aldo Milano; Alessandro Mazzucco; Giuseppe Faggian
Journal:  Heart Fail Rev       Date:  2014-05       Impact factor: 4.214

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