Literature DB >> 16820256

A patient using ziprasidone with polydipsia, seizure, hyponatremia and rhabdomyolysis.

Cengiz Akkaya1, Asli Sarandol, Enver Y Sivrioglu, Zeynep Kotan, Selcuk Kirli.   

Abstract

We aimed to report a case with rhabdomyolysis related to hyponatremia and/or its correction. A 32-year-old male schizophrenic patient on ziprasidone treatment was admitted to the hospital following a seizure. Patient had primary polydipsia and secondarily developed hyponatremia. After the correction of hyponatremia, due to the high liver enzyme levels, he was diagnosed as rhabdomyolysis. Although the role of antipsychotics in this situation is speculative, development of rhabdomyolysis related to hyponatremia and/or its correction should not be underestimated and should be assessed thoroughly.

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Year:  2006        PMID: 16820256     DOI: 10.1016/j.pnpbp.2006.05.020

Source DB:  PubMed          Journal:  Prog Neuropsychopharmacol Biol Psychiatry        ISSN: 0278-5846            Impact factor:   5.067


  5 in total

1.  Antipsychotic use is a risk factor for hyponatremia in patients with schizophrenia: a 15-year follow-up study.

Authors:  Hang-Ju Yang; Wan-Ju Cheng
Journal:  Psychopharmacology (Berl)       Date:  2017-01-11       Impact factor: 4.530

2.  Rhabdomyolysis Possibly Triggered by Clozapine, Paliperidone, Hyponatremia, and Rapid Correction of Hyponatremia: A Case Report.

Authors:  Myriam Lemelin; Nicolas Gagnon; Emmanuelle Jacques; Philippe Sirois; Alexandrine Coulombe
Journal:  Can J Hosp Pharm       Date:  2022-04-04

Review 3.  Antipsychotic-induced hyponatraemia: a systematic review of the published evidence.

Authors:  Didier Meulendijks; Cyndie K Mannesse; Paul A F Jansen; Rob J van Marum; Toine C G Egberts
Journal:  Drug Saf       Date:  2010-02-01       Impact factor: 5.606

Review 4.  Hyponatremia in Association With Second-Generation Antipsychotics: A Systematic Review of Case Reports.

Authors:  Sarah Naz Ali; Lydia A Bazzano
Journal:  Ochsner J       Date:  2018

5.  Association between rapid serum sodium correction and rhabdomyolysis in water intoxication: a retrospective cohort study.

Authors:  Masahiro Kashiura; Kazuhiro Sugiyama; Yuichi Hamabe
Journal:  J Intensive Care       Date:  2017-06-19
  5 in total

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