| Literature DB >> 16819861 |
Jiangyun Wang1, Jianming Xie, Peter G Schultz.
Abstract
The fluorescent amino acid l-(7-hydroxycoumarin-4-yl) ethylglycine 1 has been genetically encoded in E. coli in response to the amber TAG codon. Because of its high fluorescence quantum yield, relatively large Stoke's shift, and sensitivity to both pH and polarity, this amino acid should provide a useful probe of protein localization and trafficking, protein conformation changes, and protein-protein interactions.Entities:
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Year: 2006 PMID： 16819861 DOI： 10.1021/ja062666k
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419