Literature DB >> 16806510

Synaptic plasticity: one STEP at a time.

Steven P Braithwaite1, Surojit Paul, Angus C Nairn, Paul J Lombroso.   

Abstract

Striatal enriched tyrosine phosphatase (STEP) has recently been identified as a crucial player in the regulation of synaptic function. It is restricted to neurons within the CNS and acts by downregulating the activity of MAP kinases, the tyrosine kinase Fyn and NMDA receptors. By modulating these substrates, STEP acts on several parallel pathways that impact upon the progression of synaptic plasticity. Here, we review recent advances that demonstrate the importance of STEP in normal cognitive function, and its possible involvement in cognitive disorders such as Alzheimer's disease.

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Year:  2006        PMID： 16806510      PMCID： PMC1630769          DOI： 10.1016/j.tins.2006.06.007

Source DB:  PubMed          Journal:  Trends Neurosci        ISSN： 0166-2236            Impact factor:   13.837


  49 in total

Review 1.  Postsynaptic protein phosphorylation and LTP.

Authors:  T R Soderling; V A Derkach
Journal:  Trends Neurosci       Date:  2000-02       Impact factor: 13.837

2.  Activation of ERK/MAP kinase in the amygdala is required for memory consolidation of pavlovian fear conditioning.

Authors:  G E Schafe; C M Atkins; M W Swank; E P Bauer; J D Sweatt; J E LeDoux
Journal:  J Neurosci       Date:  2000-11-01       Impact factor: 6.167

Review 3.  Receptor trafficking and synaptic plasticity.

Authors:  Graham L Collingridge; John T R Isaac; Yu Tian Wang
Journal:  Nat Rev Neurosci       Date:  2004-12       Impact factor: 34.870

4.  The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway.

Authors:  S Paul; G L Snyder; H Yokakura; M R Picciotto; A C Nairn; P J Lombroso
Journal:  J Neurosci       Date:  2000-08-01       Impact factor: 6.167

5.  Hypoxia-ischemia in perinatal rat brain induces the formation of a low molecular weight isoform of striatal enriched tyrosine phosphatase (STEP).

Authors:  J W Gurd; N Bissoon; T H Nguyen; P J Lombroso; C C Rider; P W Beesley; S J Vannucci
Journal:  J Neurochem       Date:  1999-11       Impact factor: 5.372

6.  Calcium-dependent cleavage of striatal enriched tyrosine phosphatase (STEP).

Authors:  T H Nguyen; S Paul; Y Xu; J W Gurd; P J Lombroso
Journal:  J Neurochem       Date:  1999-11       Impact factor: 5.372

7.  Memory consolidation of auditory pavlovian fear conditioning requires protein synthesis and protein kinase A in the amygdala.

Authors:  G E Schafe; J E LeDoux
Journal:  J Neurosci       Date:  2000-09-15       Impact factor: 6.167

8.  Tyrosine phosphorylation of the N-methyl-D-aspartate receptor by exogenous and postsynaptic density-associated Src-family kinases.

Authors:  H H Cheung; J W Gurd
Journal:  J Neurochem       Date:  2001-08       Impact factor: 5.372

Review 9.  Synaptic plasticity in the lateral amygdala: a cellular hypothesis of fear conditioning.

Authors:  H T Blair; G E Schafe; E P Bauer; S M Rodrigues; J E LeDoux
Journal:  Learn Mem       Date:  2001 Sep-Oct       Impact factor: 2.460

10.  Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.

Authors:  Jeannie Chin; Jorge J Palop; Jukka Puoliväli; Catherine Massaro; Nga Bien-Ly; Hilary Gerstein; Kimberly Scearce-Levie; Eliezer Masliah; Lennart Mucke
Journal:  J Neurosci       Date:  2005-10-19       Impact factor: 6.167
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  58 in total

Review 1.  Synapses and Alzheimer's disease.

Authors:  Morgan Sheng; Bernardo L Sabatini; Thomas C Südhof
Journal:  Cold Spring Harb Perspect Biol       Date:  2012-05-01       Impact factor: 10.005

2.  Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.

Authors:  Pradeep Kurup; Yongfang Zhang; Jian Xu; Deepa V Venkitaramani; Vahram Haroutunian; Paul Greengard; Angus C Nairn; Paul J Lombroso
Journal:  J Neurosci       Date:  2010-04-28       Impact factor: 6.167

3.  CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice.

Authors:  Tomomi Kiyota; Satoshi Okuyama; Russell J Swan; Michael T Jacobsen; Howard E Gendelman; Tsuneya Ikezu
Journal:  FASEB J       Date:  2010-04-06       Impact factor: 5.191

4.  A STEP forward in neural function and degeneration.

Authors:  Matthew L Baum; Pradeep Kurup; Jian Xu; Paul J Lombroso
Journal:  Commun Integr Biol       Date:  2010-09

Review 5.  Beta-amyloid modulation of synaptic transmission and plasticity.

Authors:  Deepa V Venkitaramani; Jeannie Chin; William J Netzer; Gunnar K Gouras; Sylvain Lesne; Roberto Malinow; Paul J Lombroso
Journal:  J Neurosci       Date:  2007-10-31       Impact factor: 6.167

6.  Dopamine-dependent tuning of striatal inhibitory synaptogenesis.

Authors:  Darren Goffin; Afia B Ali; Nazir Rampersaud; Alexander Harkavyi; Celine Fuchs; Peter S Whitton; Angus C Nairn; Jasmina N Jovanovic
Journal:  J Neurosci       Date:  2010-02-24       Impact factor: 6.167

7.  Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization.

Authors:  Yongfang Zhang; Pradeep Kurup; Jian Xu; George M Anderson; Paul Greengard; Angus C Nairn; Paul J Lombroso
Journal:  J Neurochem       Date:  2011-09-21       Impact factor: 5.372

Review 8.  Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome.

Authors:  Elizabeth M Berry-Kravis; Lothar Lindemann; Aia E Jønch; George Apostol; Mark F Bear; Randall L Carpenter; Jacqueline N Crawley; Aurore Curie; Vincent Des Portes; Farah Hossain; Fabrizio Gasparini; Baltazar Gomez-Mancilla; David Hessl; Eva Loth; Sebastian H Scharf; Paul P Wang; Florian Von Raison; Randi Hagerman; Will Spooren; Sébastien Jacquemont
Journal:  Nat Rev Drug Discov       Date:  2017-12-08       Impact factor: 84.694

Review 9.  Delineating the mechanism of Alzheimer's disease A beta peptide neurotoxicity.

Authors:  Roberto Cappai; Kevin J Barnham
Journal:  Neurochem Res       Date:  2007-08-31       Impact factor: 3.996

10.  Alterations in STriatal-Enriched protein tyrosine Phosphatase expression, activation, and downstream signaling in early and late stages of the YAC128 Huntington's disease mouse model.

Authors:  Clare M Gladding; Jing Fan; Lily Y J Zhang; Liang Wang; Jian Xu; Edward H Y Li; Paul J Lombroso; Lynn A Raymond
Journal:  J Neurochem       Date:  2014-04-02       Impact factor: 5.372
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