Literature DB >> 16793376

Characterization of the "mismatch repairosome" and its role in the processing of modified nucleosides in vitro.

Katja Baerenfaller1, Franziska Fischer, Josef Jiricny.   

Abstract

The process of postreplicative mismatch repair (MMR) increases the fidelity of DNA replication by eliminating biosynthetic errors from newly synthesized DNA. In addition, MMR proteins are also involved in the processing of intermediates of mitotic and meiotic recombination and, in mammalian cells, play a role in DNA damage signaling. As mismatches cannot be induced in the DNA of living cells, the study of the molecular transactions during MMR is restricted to in vitro systems. This chapter describes the construction of heteroduplex substrates that can be used for DNA affinity purification of MMR protein complexes and for the study of the role of eukaryotic MMR proteins in the processing of modified nucleosides.

Entities:  

Mesh：

Substances：

Year:  2006        PMID： 16793376     DOI： 10.1016/S0076-6879(06)08018-9

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


  11 in total

1.  Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair.

Authors:  Nicolaas Hermans; Charlie Laffeber; Michele Cristovão; Mariela Artola-Borán; Yannicka Mardenborough; Pauline Ikpa; Aruna Jaddoe; Herrie H K Winterwerp; Claire Wyman; Josef Jiricny; Roland Kanaar; Peter Friedhoff; Joyce H G Lebbink
Journal:  Nucleic Acids Res       Date:  2016-05-12       Impact factor: 16.971

2.  Interplay between mismatch repair and chromatin assembly.

Authors:  Barbara Schöpf; Stephanie Bregenhorn; Jean-Pierre Quivy; Farid A Kadyrov; Genevieve Almouzni; Josef Jiricny
Journal:  Proc Natl Acad Sci U S A       Date:  2012-01-09       Impact factor: 11.205

3.  Influence of oxidized purine processing on strand directionality of mismatch repair.

Authors:  Simone Repmann; Maite Olivera-Harris; Josef Jiricny
Journal:  J Biol Chem       Date:  2015-02-18       Impact factor: 5.157

4.  Ectopic Methylation of a Single Persistently Unmethylated CpG in the Promoter of the Vitellogenin Gene Abolishes Its Inducibility by Estrogen through Attenuation of Upstream Stimulating Factor Binding.

Authors:  Lia Kallenberger; Rachel Erb; Lucie Kralickova; Andrea Patrignani; Esther Stöckli; Josef Jiricny
Journal:  Mol Cell Biol       Date:  2019-11-12       Impact factor: 4.272

5.  Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands.

Authors:  Ibtissam Talhaoui; Sophie Couve; Laurent Gros; Alexander A Ishchenko; Bakhyt Matkarimov; Murat K Saparbaev
Journal:  Nucleic Acids Res       Date:  2014-04-01       Impact factor: 16.971

6.  Large-scale preparation of fluorescence multiplex host cell reactivation (FM-HCR) reporters.

Authors:  C G Piett; T J Pecen; D J Laverty; Z D Nagel
Journal:  Nat Protoc       Date:  2021-08-06       Impact factor: 17.021

7.  MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.

Authors:  Flora S Groothuizen; Ines Winkler; Michele Cristóvão; Alexander Fish; Herrie H K Winterwerp; Annet Reumer; Andreas D Marx; Nicolaas Hermans; Robert A Nicholls; Garib N Murshudov; Joyce H G Lebbink; Peter Friedhoff; Titia K Sixma
Journal:  Elife       Date:  2015-07-11       Impact factor: 8.140

8.  The Saccharomyces cerevisiae Dna2 can function as a sole nuclease in the processing of Okazaki fragments in DNA replication.

Authors:  Maryna Levikova; Petr Cejka
Journal:  Nucleic Acids Res       Date:  2015-07-14       Impact factor: 16.971

9.  Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair.

Authors:  Medini Manohar Ghodgaonkar; Federico Lazzaro; Maite Olivera-Pimentel; Mariela Artola-Borán; Petr Cejka; Martin A Reijns; Andrew P Jackson; Paolo Plevani; Marco Muzi-Falconi; Josef Jiricny
Journal:  Mol Cell       Date:  2013-04-18       Impact factor: 17.970

10.  Biochemical characterization of a cancer-associated E109K missense variant of human exonuclease 1.

Authors:  Stephanie Bregenhorn; Josef Jiricny
Journal:  Nucleic Acids Res       Date:  2014-05-14       Impact factor: 16.971
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.