| Literature DB >> 16792424 |
Gustavo Moura-Letts1, León F Villegas, Ana Marçalo, Abraham J Vaisberg, Gerald B Hammond.
Abstract
Anredera diffusa is used as a wound-healing agent in traditional Peruvian medicine. Acid hydrolysis of the bioactive ethanolic extract, followed by in vivo activity-guided fractionation, yielded oleanolic acid, with a wound-healing activity equivalent to 42.9% (p < 0.01) above the control. The highest cicatrizant activity in mice was obtained by applying 40 microg of oleanolic acid per gram of body weight.Entities:
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Year: 2006 PMID: 16792424 DOI: 10.1021/np0601152
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050