Literature DB >> 16792424

In vivo wound-healing activity of oleanolic acid derived from the acid hydrolysis of Anredera diffusa.

Gustavo Moura-Letts1, León F Villegas, Ana Marçalo, Abraham J Vaisberg, Gerald B Hammond.   

Abstract

Anredera diffusa is used as a wound-healing agent in traditional Peruvian medicine. Acid hydrolysis of the bioactive ethanolic extract, followed by in vivo activity-guided fractionation, yielded oleanolic acid, with a wound-healing activity equivalent to 42.9% (p < 0.01) above the control. The highest cicatrizant activity in mice was obtained by applying 40 microg of oleanolic acid per gram of body weight.

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Year:  2006        PMID: 16792424     DOI: 10.1021/np0601152

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  10 in total

1.  Areca catechu L. and Anredera cordifolia (Ten) Steenis supplementation reduces faecal parasites and improves caecal histopathology in laying hens.

Authors:  Retno Murwani; Endang Kusumanti; Elena N Naumova
Journal:  Int J Vet Sci Med       Date:  2022-07-07

Review 2.  A multipronged approach to the study of peruvian ethnomedicinal plants: a legacy of the ICBG-Peru Project.

Authors:  José C Aponte; Abraham J Vaisberg; Rosario Rojas; Michel Sauvain; Walter H Lewis; Gerardo Lamas; César Sarasara; Robert H Gilman; Gerald B Hammond
Journal:  J Nat Prod       Date:  2009-03-27       Impact factor: 4.050

Review 3.  Wound Healing Property Review of Siam Weed, Chromolaena odorata.

Authors:  Anushika Sirinthipaporn; Wannee Jiraungkoorskul
Journal:  Pharmacogn Rev       Date:  2017 Jan-Jun

4.  Oleanolic acid induces migration in Mv1Lu and MDA-MB-231 epithelial cells involving EGF receptor and MAP kinases activation.

Authors:  Ángel Bernabé-García; David Armero-Barranco; Sergio Liarte; María Ruzafa-Martínez; Antonio Jesús Ramos-Morcillo; Francisco José Nicolás
Journal:  PLoS One       Date:  2017-02-23       Impact factor: 3.240

Review 5.  Tetracyclic and Pentacyclic Triterpenes with High Therapeutic Efficiency in Wound Healing Approaches.

Authors:  Roxana Ghiulai; Oana Janina Roşca; Diana Simona Antal; Marius Mioc; Alexandra Mioc; Roxana Racoviceanu; Ioana Macaşoi; Tudor Olariu; Cristina Dehelean; Octavian Marius Creţu; Mirela Voicu; Codruţa Şoica
Journal:  Molecules       Date:  2020-11-26       Impact factor: 4.411

6.  Oleanolic acid stimulation of cell migration involves a biphasic signaling mechanism.

Authors:  Javier Stelling-Férez; José Antonio Gabaldón; Francisco José Nicolás
Journal:  Sci Rep       Date:  2022-09-05       Impact factor: 4.996

Review 7.  A Comprehensive Review of Natural Compounds for Wound Healing: Targeting Bioactivity Perspective.

Authors:  Xuan-Tung Trinh; Nguyen-Van Long; Le Thi Van Anh; Pham Thi Nga; Nguyen Ngan Giang; Pham Ngoc Chien; Sun-Young Nam; Chan-Yeong Heo
Journal:  Int J Mol Sci       Date:  2022-08-24       Impact factor: 6.208

8.  Effects of Lipophilic Extract of Viscum album L. and Oleanolic Acid on Migratory Activity of NIH/3T3 Fibroblasts and on HaCat Keratinocytes.

Authors:  R Kuonen; U Weissenstein; K Urech; M Kunz; K Hostanska; M Estko; P Heusser; S Baumgartner
Journal:  Evid Based Complement Alternat Med       Date:  2013-11-26       Impact factor: 2.629

9.  Discovery of triterpenoids as reversible inhibitors of α/β-hydrolase domain containing 12 (ABHD12).

Authors:  Teija Parkkari; Raisa Haavikko; Tuomo Laitinen; Dina Navia-Paldanius; Roosa Rytilahti; Miia Vaara; Marko Lehtonen; Sami Alakurtti; Jari Yli-Kauhaluoma; Tapio Nevalainen; Juha R Savinainen; Jarmo T Laitinen
Journal:  PLoS One       Date:  2014-05-30       Impact factor: 3.240

10.  Influence of the Oil Phase and Topical Formulation on the Wound Healing Ability of a Birch Bark Dry Extract.

Authors:  Isabel Steinbrenner; Pia Houdek; Simone Pollok; Johanna M Brandner; Rolf Daniels
Journal:  PLoS One       Date:  2016-05-24       Impact factor: 3.240

  10 in total

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