Literature DB >> 16785290

Life-threatening sepsis caused by Burkholderia cepacia from contaminated intravenous flush solutions prepared by a compounding pharmacy in another state.

Melissa R Held1, Elizabeth M Begier, Diana S Beardsley, Frederick A Browne, Richard A Martinello, Robert S Baltimore, L Clifford McDonald, Bette Jensen, James L Hadler, Louise-Marie Dembry.   

Abstract

We report 2 life-threatening cases of Burkholderia cepacia sepsis caused by infusate contamination during compounding. Bacterial isolates from the patients' blood cultures and the infusate were indistinguishable by pulsed-field gel electrophoresis. Proper quality controls at a local and national level are important for ensuring safe delivery of compounded medications to patients in all settings, including those outside health care facilities.

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Year:  2006        PMID： 16785290     DOI： 10.1542/peds.2005-2617

Source DB:  PubMed          Journal:  Pediatrics        ISSN： 0031-4005            Impact factor:   7.124


  12 in total

1.  Optimal media for use in air sampling to detect cultivable bacteria and fungi in the pharmacy.

Authors:  Alice S Weissfeld; Riya Augustin Joseph; Theresa V Le; Ernest A Trevino; M Frances Schaeffer; Paula H Vance
Journal:  J Clin Microbiol       Date:  2013-07-31       Impact factor: 5.948

Review 2.  Straight from the headlines: what is going on in compounding pharmacies, and how can clinical microbiologists help?

Authors:  Alice S Weissfeld
Journal:  J Clin Microbiol       Date:  2013-06-19       Impact factor: 5.948

3.  An outbreak of Burkholderia cenocepacia bacteremia in immunocompromised oncology patients.

Authors:  T Mann; D Ben-David; A Zlotkin; D Shachar; N Keller; A Toren; A Nagler; G Smollan; A Barzilai; G Rahav
Journal:  Infection       Date:  2010-04-01       Impact factor: 3.553

Review 4.  U.S. Compounding Pharmacy-Related Outbreaks, 2001-2013: Public Health and Patient Safety Lessons Learned.

Authors:  Nadine Shehab; Megan N Brown; Alexander J Kallen; Joseph F Perz
Journal:  J Patient Saf       Date:  2018-09       Impact factor: 2.844

5.  Achromobacter spp. bacteremia outbreak related to contaminated furosemide ampoules.

Authors:  Rajalakshmi Arjun; Kalpana E John; Vettakkara Kandy Muhammed Niyas; Sreerekha R Nair; Viji Mohan; Raveendran Sarala Ratheesh
Journal:  Infez Med       Date:  2021-09-10

6.  A pseudo-outbreak of Burkholderia cepacia complex in a Kentucky hospital.

Authors:  Chad C Eldridge; Andrea H Flinchum; Doug Thoroughman; Kevin B Spicer
Journal:  Am J Infect Control       Date:  2021-11-03       Impact factor: 2.918

Review 7.  Description of outbreaks of health-care-associated infections related to compounding pharmacies, 2000-12.

Authors:  Catherine Staes; Jason Jacobs; Jeanmarie Mayer; Jill Allen
Journal:  Am J Health Syst Pharm       Date:  2013-08-01       Impact factor: 2.637

8.  Outbreak of Serratia marcescens bloodstream infections in patients receiving parenteral nutrition prepared by a compounding pharmacy.

Authors:  Neil Gupta; Susan N Hocevar; Heather A Moulton-Meissner; Kelly M Stevens; Mary G McIntyre; Bette Jensen; David T Kuhar; Judith A Noble-Wang; Rick G Schnatz; Shawn C Becker; Eric S Kastango; Nadine Shehab; Alexander J Kallen
Journal:  Clin Infect Dis       Date:  2014-04-11       Impact factor: 9.079

9.  Sphingomonas paucimobilis bloodstream infections associated with contaminated intravenous fentanyl.

Authors:  Lisa L Maragakis; Romanee Chaiwarith; Arjun Srinivasan; Francesca J Torriani; Edina Avdic; Andrew Lee; Tracy R Ross; Karen C Carroll; Trish M Perl
Journal:  Emerg Infect Dis       Date:  2009-01       Impact factor: 6.883

Review 10.  Potential risks of pharmacy compounding.

Authors:  Jennifer Gudeman; Michael Jozwiakowski; John Chollet; Michael Randell
Journal:  Drugs R D       Date:  2013-03
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