| Literature DB >> 16779479 |
Ian R Baxendale1, Jon Deeley, Charlotte M Griffiths-Jones, Steven V Ley, Steen Saaby, Geoffrey K Tranmer.
Abstract
A flow process for the multi-step synthesis of the alkaloid natural product (+/-)-oxomaritidine is described, mediated through the use of microfluidic pumping systems that progress material through various packed columns containing immobilized reagents, catalysts, scavengers or catch and release agents; our route involves the combination of seven separate synthetic steps linked into one continuous sequence utilizing flow chemistry.Entities:
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Year: 2006 PMID： 16779479 DOI： 10.1039/b600382f
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222