Literature DB >> 16779120

Use of description logic classification to reason about consequences of penetrating injuries.

Daniel L Rubin1, Olivier Dameron, Mark A Musen.   

Abstract

The consequences of penetrating injuries can be complex, including abnormal blood flow through the injury channel and functional impairment of organs if arteries supplying them have been severed. Determining the consequences of such injuries can be posed as a classification problem, requiring a priori symbolic knowledge of anatomy. We hypothesize that such symbolic knowledge can be modeled using ontologies, and that the reasoning task can be accomplished using knowl-edge representation in description logics (DL) and automatic classification. We demonstrate the capabilities of automated classification using the Web Ontology Language (OWL) to reason about the consequences of penetrating injuries. We created in OWL a knowledge model of chest and heart anatomy describing the heart structure and the surrounding anatomic compartments, as well as the perfusion of regions of the heart by branches of the coronary arteries. We then used a domain-independent classifier to infer ischemic regions of the heart as well as anatomic spaces containing ectopic blood secondary to the injuries. Our results highlight the advantages of posing reasoning problems as a classification task, and lever-aging the automatic classification capabilities of DL to create intelligent applications.

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Mesh:

Year:  2005        PMID: 16779120      PMCID: PMC1560440     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  5 in total

1.  A reference ontology for biomedical informatics: the Foundational Model of Anatomy.

Authors:  Cornelius Rosse; José L V Mejino
Journal:  J Biomed Inform       Date:  2003-12       Impact factor: 6.317

2.  Evolution of a Foundational Model of Physiology: symbolic representation for functional bioinformatics.

Authors:  Daniel L Cook; Jose L V Mejino; Cornelius Rosse
Journal:  Stud Health Technol Inform       Date:  2004

3.  Challenges in converting frame-based ontology into OWL: the Foundational Model of Anatomy case-study.

Authors:  Olivier Dameron; Daniel L Rubin; Mark A Musen
Journal:  AMIA Annu Symp Proc       Date:  2005

4.  Computer-generated trauma management plans: comparison with actual care.

Authors:  John R Clarke; Catherine Z Hayward; Thomas A Santora; David K Wagner; Bonnie L Webber
Journal:  World J Surg       Date:  2002-02-13       Impact factor: 3.352

5.  NCI Thesaurus: using science-based terminology to integrate cancer research results.

Authors:  Sherri de Coronado; Margaret W Haber; Nicholas Sioutos; Mark S Tuttle; Lawrence W Wright
Journal:  Stud Health Technol Inform       Date:  2004
  5 in total
  5 in total

1.  An ontology for PACS integration.

Authors:  Charles E Kahn; David S Channin; Daniel L Rubin
Journal:  J Digit Imaging       Date:  2006-12       Impact factor: 4.056

2.  Challenges in converting frame-based ontology into OWL: the Foundational Model of Anatomy case-study.

Authors:  Olivier Dameron; Daniel L Rubin; Mark A Musen
Journal:  AMIA Annu Symp Proc       Date:  2005

3.  Translating the Foundational Model of Anatomy into OWL.

Authors:  Natalya F Noy; Daniel L Rubin
Journal:  Web Semant       Date:  2008       Impact factor: 1.897

4.  A prototype symbolic model of canonical functional neuroanatomy of the motor system.

Authors:  Ion-Florin Talos; Daniel L Rubin; Michael Halle; Mark Musen; Ron Kikinis
Journal:  J Biomed Inform       Date:  2007-11-22       Impact factor: 6.317

5.  Using description logics to evaluate the consistency of drug-class membership relations in NDF-RT.

Authors:  Rainer Winnenburg; Jonathan M Mortensen; Olivier Bodenreider
Journal:  J Biomed Semantics       Date:  2015-03-28
  5 in total

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