Literature DB >> 1677905

Sequence analysis of a Staphylococcus aureus gene encoding a peptidoglycan hydrolase activity.

X Wang1, B J Wilkinson, R K Jayaswal.   

Abstract

The nucleotide (nt) sequence of a 2.0-kb NheI-XbaI DNA fragment containing a peptidoglycan hydrolase-encoding gene, lytA, tentatively identified as encoding an N-acetylmuramyl-L-alanine amidase, from Staphylococcus aureus, was determined. The nt sequencing revealed an open reading frame (ORF) of 1443 bp with a consensus ribosome-binding site located 7 nt upstream from the ATG start codon. The primary amino acid (aa) sequence deduced from the nt sequence revealed a putative protein of 481 aa residues with an Mr of 53815. Comparison of the aa sequence of the ORF with aa sequences in the GenBank data base (version 63, March 1990) revealed that the C-terminal sequence showed significant homology to the C-terminal sequence of lysostaphin from Staphylococcus simulans biovar staphylolyticus.

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Year:  1991        PMID： 1677905     DOI： 10.1016/0378-1119(91)90547-o

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  20 in total

1.  Enterolysin A, a cell wall-degrading bacteriocin from Enterococcus faecalis LMG 2333.

Authors:  Trine Nilsen; Ingolf F Nes; Helge Holo
Journal:  Appl Environ Microbiol       Date:  2003-05       Impact factor: 4.792

2.  Analysis of a peptidoglycan hydrolase gene from Staphylococcus aureus NCTC 8325.

Authors:  X Wang; N Mani; P A Pattee; B J Wilkinson; R K Jayaswal
Journal:  J Bacteriol       Date:  1992-10       Impact factor: 3.490

3.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1991-11-25       Impact factor: 16.971

4.  Identification and characterization of a lysis module present in a large proportion of bacteriophages infecting Streptococcus thermophilus.

Authors:  M M Sheehan; E Stanley; G F Fitzgerald; D van Sinderen
Journal:  Appl Environ Microbiol       Date:  1999-02       Impact factor: 4.792

5.  Staphylococcus caprae strains carry determinants known to be involved in pathogenicity: a gene encoding an autolysin-binding fibronectin and the ica operon involved in biofilm formation.

Authors:  J Allignet; S Aubert; K G Dyke; N El Solh
Journal:  Infect Immun       Date:  2001-02       Impact factor: 3.441

6.  Molecular cloning, sequencing, and expression of lytM, a unique autolytic gene of Staphylococcus aureus.

Authors:  L Ramadurai; R K Jayaswal
Journal:  J Bacteriol       Date:  1997-06       Impact factor: 3.490

7.  Staphylococcus haemolyticus prophage ΦSH2 endolysin relies on cysteine, histidine-dependent amidohydrolases/peptidases activity for lysis 'from without'.

Authors:  Mathias Schmelcher; Olga Korobova; Nina Schischkova; Natalia Kiseleva; Paul Kopylov; Sergey Pryamchuk; David M Donovan; Igor Abaev
Journal:  J Biotechnol       Date:  2012-09-28       Impact factor: 3.307

8.  Target cell specificity of a bacteriocin molecule: a C-terminal signal directs lysostaphin to the cell wall of Staphylococcus aureus.

Authors:  T Baba; O Schneewind
Journal:  EMBO J       Date:  1996-09-16       Impact factor: 11.598

9.  Discovery of novel S. aureus autolysins and molecular engineering to enhance bacteriolytic activity.

Authors:  Daniel C Osipovitch; Sophie Therrien; Karl E Griswold
Journal:  Appl Microbiol Biotechnol       Date:  2015-02-18       Impact factor: 4.813

10.  Isolation and characterization of autolysis-defective mutants of Staphylococcus aureus created by Tn917-lacZ mutagenesis.

Authors:  N Mani; P Tobin; R K Jayaswal
Journal:  J Bacteriol       Date:  1993-03       Impact factor: 3.490
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