Literature DB >> 16775240

Circumventing resistance to kinase-inhibitor therapy.

Brian J Druker.   

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Year:  2006        PMID: 16775240     DOI: 10.1056/NEJMe068073

Source DB:  PubMed          Journal:  N Engl J Med        ISSN: 0028-4793            Impact factor:   91.245


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  45 in total

1.  A positive role for c-Abl in Atm and Atr activation in DNA damage response.

Authors:  X Wang; L Zeng; J Wang; J F L Chau; K P Lai; D Jia; A Poonepalli; M P Hande; H Liu; G He; L He; B Li
Journal:  Cell Death Differ       Date:  2010-08-27       Impact factor: 15.828

2.  Imatinib spells BAD news for Bcr/abl-positive leukemias.

Authors:  Scott H Kaufmann
Journal:  Proc Natl Acad Sci U S A       Date:  2006-09-26       Impact factor: 11.205

3.  Drug discovery in jeopardy.

Authors:  Pedro Cuatrecasas
Journal:  J Clin Invest       Date:  2006-11       Impact factor: 14.808

Review 4.  Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of central nervous system metastases from non-small cell lung cancer: the present and the future.

Authors:  Claudia Proto; Martina Imbimbo; Rosaria Gallucci; Angela Brissa; Diego Signorelli; Milena Vitali; Marianna Macerelli; Giulia Corrao; Monica Ganzinelli; Francesca Gabriella Greco; Marina Chiara Garassino; Giuseppe Lo Russo
Journal:  Transl Lung Cancer Res       Date:  2016-12

Review 5.  Kinase packing defects as drug targets.

Authors:  Alejandro Crespo; Ariel Fernández
Journal:  Drug Discov Today       Date:  2007-10-30       Impact factor: 7.851

6.  Rational drug redesign to overcome drug resistance in cancer therapy: imatinib moving target.

Authors:  Ariel Fernández; Angela Sanguino; Zhenghong Peng; Alejandro Crespo; Eylem Ozturk; Xi Zhang; Shimei Wang; William Bornmann; Gabriel Lopez-Berestein
Journal:  Cancer Res       Date:  2007-05-01       Impact factor: 12.701

7.  Ligand binding and protein dynamics in lactate dehydrogenase.

Authors:  J R Exequiel T Pineda; Robert Callender; Steven D Schwartz
Journal:  Biophys J       Date:  2007-05-04       Impact factor: 4.033

Review 8.  BCR-ABL truncation due to premature translation termination as a mechanism of resistance to kinase inhibitors.

Authors:  Wanlong Ma; Hagop Kantarjian; Chen-Hsiung Yeh; Zhong J Zhang; Jorge Cortes; Maher Albitar
Journal:  Acta Haematol       Date:  2009-03-31       Impact factor: 2.195

9.  Effective killing of Gleevec-resistant CML cells with T315I mutation by a natural compound PEITC through redox-mediated mechanism.

Authors:  H Zhang; D Trachootham; W Lu; J Carew; F J Giles; M J Keating; R B Arlinghaus; P Huang
Journal:  Leukemia       Date:  2008-04-03       Impact factor: 11.528

10.  Development and validation of a sensitive assay for the quantification of imatinib using LC/LC-MS/MS in human whole blood and cell culture.

Authors:  Jelena Klawitter; Yan Ling Zhang; Jost Klawitter; Nora Anderson; Natalie J Serkova; Uwe Christians
Journal:  Biomed Chromatogr       Date:  2009-12       Impact factor: 1.902

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