Literature DB >> 16773263

Sensitivity and specificity of intraoperative recurrent laryngeal nerve stimulation test for predicting vocal cord palsy after thyroid surgery.

Chisato Tomoda1, Yoshihiro Hirokawa, Takashi Uruno, Yuuki Takamura, Yasuhiro Ito, Akihiro Miya, Kaoru Kobayashi, Fumio Matsuzuka, Kanji Kuma, Akira Miyauchi.   

Abstract

INTRODUCTION: Recurrent laryngeal nerve (RLN) palsy after thyroidectomy, although infrequently encountered, can decrease quality of life. In addition to the hoarseness that occurs with unilateral RLN palsy, bilateral RLN palsy leads to dyspnea and often to life-threatening glottal obstruction. Therefore, intraoperative awareness of the nerve's status is of great importance. This study examined the sensitivity and specificity of a palpation technique to detect contraction of the posterior cricoarytenoid muscle (PCA) through the posterior hypopharyngeal wall while the RLN was being stimulated with a disposable nerve stimulator during thyroid surgery (the laryngeal palpation test) to predict postoperative RLN deficits.
METHODS: A total of 2197 RLNs in 1376 patients were identified to be at risk of injury during thyroidectomy performed between July 2003 and August 2004. Postoperative RLN integrity was assessed using direct laryngoscopy or laryngofiberoscopy to visualize vocal fold mobility.
RESULTS: Altogether, 76 RLNs failed to elicit a PCA contraction in response to nerve stimulation, and 80 cases of temporary vocal cord palsy and 21 cases of permanent vocal cord palsy were recognized on postoperative evaluation. For postoperative vocal cord palsy, the sensitivity and specificity of the laryngeal palpation test were 69.3% and 99.7%, respectively, with a positive predictive value of 92.1% and negative predictive value of 98.5%. For permanent vocal cord palsy, the sensitivity and specificity were 85.7% and 97.3%, respectively, with a positive predictive value of 23.7% and negative predictive value of 99.8%.
CONCLUSIONS: The laryngeal palpation test is not a particularly useful method for predicting the level of RLN function after thyroidectomy. All patients must be examined postoperatively by direct laryngoscopy or laryngofiberoscopy to check vocal cord mobility. Even if there is no contraction of the PCA and we detect vocal cord palsy immediately after surgery, vocal cord palsy often recovers within 1 year when visual preservation of RLN is successful.

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Year:  2006        PMID: 16773263     DOI: 10.1007/s00268-005-0351-z

Source DB:  PubMed          Journal:  World J Surg        ISSN: 0364-2313            Impact factor:   3.352


  14 in total

1.  Evaluation of intraoperative recurrent nerve monitoring in thyroid surgery.

Authors:  Guido Beldi; Thomas Kinsbergen; Rolf Schlumpf
Journal:  World J Surg       Date:  2004-06       Impact factor: 3.352

2.  Recurrent laryngeal nerve identification and assessment during thyroid surgery: laryngeal palpation.

Authors:  Gregory W Randolph; James B Kobler; Jamie Wilkins
Journal:  World J Surg       Date:  2004-08-03       Impact factor: 3.352

3.  Revised anatomy of the recurrent laryngeal nerves. Surgical importance based on the dissection of 100 cadavers; a preliminary report.

Authors:  W H RUSTAD; L F MORRISON
Journal:  Laryngoscope       Date:  1952-03       Impact factor: 3.325

4.  Multiple divisions of the recurrent laryngeal nerve. An anatomic study.

Authors:  W G ARMSTRONG; J W HINTON
Journal:  AMA Arch Surg       Date:  1951-04

5.  Advantages of recurrent laryngeal nerve identification in thyroidectomy and parathyroidectomy and the importance of preoperative and postoperative laryngoscopic examination in more than 1000 nerves at risk.

Authors:  Martin Steurer; Christian Passler; Doris M Denk; Berit Schneider; Bruno Niederle; Wolfgang Bigenzahn
Journal:  Laryngoscope       Date:  2002-01       Impact factor: 3.325

6.  The anatomy of the inferior laryngeal nerve.

Authors:  V Schweizer; J Dörfl
Journal:  Clin Otolaryngol Allied Sci       Date:  1997-08

7.  Extralaryngeal divisions of the recurrent laryngeal nerve. Surgical and clinical significance.

Authors:  P M Nemiroff; A D Katz
Journal:  Am J Surg       Date:  1982-10       Impact factor: 2.565

8.  Extralaryngeal division of the recurrent laryngeal nerve. Report on 400 patients and the 721 nerves measured.

Authors:  A D Katz
Journal:  Am J Surg       Date:  1986-10       Impact factor: 2.565

9.  Success of unilateral neck exploration for sporadic primary hyperparathyroidism.

Authors:  M J Worsey; S E Carty; C G Watson
Journal:  Surgery       Date:  1993-12       Impact factor: 3.982

Review 10.  Recurrent nerve palsy after thyroid operations--principal nerve identification and a literature review.

Authors:  G R Jatzko; P H Lisborg; M G Müller; V M Wette
Journal:  Surgery       Date:  1994-02       Impact factor: 3.982

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  35 in total

1.  Feasibility of intraoperative neuromonitoring during thyroid surgery after administration of nondepolarizing neuromuscular blocking agents.

Authors:  Koung-Shing Chu; Sheng-Hua Wu; I-Cheng Lu; Cheng-Jing Tsai; Che-Wei Wu; Wen-Rei Kuo; Ka-Wo Lee; Feng-Yu Chiang
Journal:  World J Surg       Date:  2009-07       Impact factor: 3.352

2.  [Intraoperative neuromonitoring in thyroid surgery. Recommendations of the Surgical Working Group for Endocrinology].

Authors:  H Dralle; K Lorenz; P Schabram; T J Musholt; C Dotzenrath; P E Goretzki; J Kußmann; B Niederle; C Nies; J Schabram; C Scheuba; D Simon; T Steinmüller; A Trupka
Journal:  Chirurg       Date:  2013-12       Impact factor: 0.955

3.  Intraoperative neural monitoring in thyroid cancer surgery.

Authors:  Gregory W Randolph; Dipti Kamani
Journal:  Langenbecks Arch Surg       Date:  2013-11-27       Impact factor: 3.445

4.  Electromyographic response persists after peripheral transection: endorsement of current concepts in recurrent laryngeal nerve monitoring in a porcine model.

Authors:  Torsten Birkholz; Andrea Irouschek; Dirk Labahn; Peter Klein; Joachim Schmidt
Journal:  Langenbecks Arch Surg       Date:  2009-11-25       Impact factor: 3.445

Review 5.  [Vocal cord paralysis after thyroid surgery : Current medicolegal aspects of intraoperative neuromonitoring].

Authors:  H Dralle; R Schneider; K Lorenz; N Thanh Phuong; C Sekulla; A Machens
Journal:  Chirurg       Date:  2015-07       Impact factor: 0.955

6.  Invited commentary on Melin et al. (doi: 10.1007/s00268-013-2260-x).

Authors:  Gerard M Doherty
Journal:  World J Surg       Date:  2014-10       Impact factor: 3.352

7.  Postoperative vocal cord dysfunction despite normal intraoperative neuromonitoring: an unexpected complication with the risk of bilateral palsy.

Authors:  Magnus Melin; Katharina Schwarz; Marc D Pearson; Bernhard J Lammers; Peter E Goretzki
Journal:  World J Surg       Date:  2014-10       Impact factor: 3.352

Review 8.  Intraoperative Neural Monitoring for Early Vocal Cord Function Assessment After Thyroid Surgery: A Systematic Review and Meta-Analysis.

Authors:  Do Hyun Kim; Sung Won Kim; Se Hwan Hwang
Journal:  World J Surg       Date:  2021-06-30       Impact factor: 3.352

9.  Monitoring of recurrent and superior laryngeal nerve function using an Airwayscope™ during thyroid surgery.

Authors:  Kei Ijichi; Hiroshi Sasano; Megumi Harima; Shingo Murakami
Journal:  Mol Clin Oncol       Date:  2017-08-18

10.  Medico legal aspects on neuromonitoring in thyroid surgery: informed consent on malpractice claims.

Authors:  R Demontis; M R Pittau; A Maturo; P Petruzzo; G Calò
Journal:  G Chir       Date:  2017 May-Jun
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