Literature DB >> 16772009

Acute undifferentiated fever in Binh Thuan province, Vietnam: imprecise clinical diagnosis and irrational pharmaco-therapy.

Hoang L Phuong1, Peter J de Vries, Nico Nagelkerke, Phan T Giao, Le Q Hung, Tran Q Binh, Tran T Thanh Nga, Nguyen V Nam, Piet A Kager.   

Abstract

OBJECTIVES: To describe the characteristics of patients consulting commune primary healthcare posts for acute undifferentiated fever not being malaria (AUF), and to explore the diagnostic and therapeutic responses of the healthcare workers.
METHODS: All patients presenting with AUF at 12 commune health posts and one clinic at the provincial malaria station, Binh Thuan, a dengue endemic province in southern Vietnam, were included. Record forms were used to fill in patient and diseases characteristics, pre-referral treatment, signs and symptoms, provisional diagnosis and installed treatment, referral and final outcome.
RESULTS: Two thousand ninety-six patients were included from April 2001 to March 2002. The median delay to attend the health posts was, 0.87 day for > 5, 1.15 days for children aged 5-15 years and 1.41 days for adults (P < 0.001). Sixty-five per cent of patients took some measures before consulting the health post, of whom 82% applied self-medication and 69% took antibiotics. Pre-referral medication with antibiotics increased with age (RR 1.012 per year of age; 95% CI: 1.004-1.019). The diagnostic and therapeutic response of healthcare workers was very unspecific. The tourniquet test was inappropriately used as general discriminating test, not only for detecting dengue haemorrhagic fever. Empiric antibiotic therapy was installed in 77.2% of cases.
CONCLUSIONS: Management of uncomplicated fever, not being malaria, at the primary healthcare level in Vietnam is non-specific, dominated by searching signs of hemorrhagic dengue and empiric antibiotic treatment. This can probably be improved by better education.

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Year:  2006        PMID: 16772009     DOI: 10.1111/j.1365-3156.2006.01636.x

Source DB:  PubMed          Journal:  Trop Med Int Health        ISSN: 1360-2276            Impact factor:   2.622


  20 in total

1.  Randomised primary health center based interventions to improve the diagnosis and treatment of undifferentiated fever and dengue in Vietnam.

Authors:  Hoang L Phuong; Tran T T Nga; Phan T Giao; Le Q Hung; Tran Q Binh; Nguyen V Nam; Nico Nagelkerke; Peter J de Vries
Journal:  BMC Health Serv Res       Date:  2010-09-21       Impact factor: 2.655

2.  Evaluation of two rapid immunochromatographic assays for diagnosis of dengue among Vietnamese febrile patients.

Authors:  Tran Thi Thanh Nga; Khoa T D Thai; Hoang Lan Phuong; Phan Trong Giao; Le Quoc Hung; Tran Quang Binh; Vo Thi Chi Mai; Nguyen Van Nam; Peter J de Vries
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3.  Acute undifferentiated febrile illness: Protocol in emergency department.

Authors:  Vempalli N Subramanyam; Nidhi Kaeley; Manish Kumar; Subodh K Pandey; Bharat B Bhardwaj; Konda S Reddy
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4.  Dengue dynamics in Binh Thuan province, southern Vietnam: periodicity, synchronicity and climate variability.

Authors:  Khoa T D Thai; Bernard Cazelles; Nam Van Nguyen; Long Thi Vo; Maciej F Boni; Jeremy Farrar; Cameron P Simmons; H Rogier van Doorn; Peter J de Vries
Journal:  PLoS Negl Trop Dis       Date:  2010-07-13

5.  Trends in patterns of dengue transmission over 4 years in a pediatric cohort study in Nicaragua.

Authors:  Angel Balmaseda; Katherine Standish; Juan Carlos Mercado; Juan Carlos Matute; Yolanda Tellez; Saira Saborío; Samantha N Hammond; Andrea Nuñez; William Avilés; Matthew R Henn; Edward C Holmes; Aubree Gordon; Josefina Coloma; Guillermina Kuan; Eva Harris
Journal:  J Infect Dis       Date:  2010-01-01       Impact factor: 5.226

6.  Irrational Antibiotic Use among Secondary School Teachers and University Faculty Members in Shiraz, Iran.

Authors:  Mehrdad Askarian; Najmeh Maharlouie
Journal:  Int J Prev Med       Date:  2012-12

7.  A protocol for the emergency department management of acute undifferentiated febrile illness in India.

Authors:  Sudhagar Thangarasu; Piruthiviraj Natarajan; Parivalavan Rajavelu; Arjun Rajagopalan; Jeremy S Seelinger Devey
Journal:  Int J Emerg Med       Date:  2011-09-05

8.  Age-specificity of clinical dengue during primary and secondary infections.

Authors:  Khoa T D Thai; Hiroshi Nishiura; Phuong Lan Hoang; Nga Thanh Thi Tran; Giao Trong Phan; Hung Quoc Le; Binh Quang Tran; Nam Van Nguyen; Peter J de Vries
Journal:  PLoS Negl Trop Dis       Date:  2011-06-21

9.  Clinical, epidemiological and virological features of Dengue virus infections in Vietnamese patients presenting to primary care facilities with acute undifferentiated fever.

Authors:  Khoa T D Thai; Hoang Lan Phuong; Tran Thi Thanh Nga; Phan Trong Giao; Le Quoc Hung; Nguyen Van Nam; Tran Quang Binh; Cameron Simmons; Jeremy Farrar; Tran Thinh Hien; H Rogier van Doorn; Menno D de Jong; Peter J de Vries
Journal:  J Infect       Date:  2010-01-18       Impact factor: 6.072

10.  Frequency and clinical features of dengue infection in a schoolchildren cohort from medellin, Colombia.

Authors:  Berta Nelly Restrepo; Leidy Diana Piedrahita; Ivony Yireth Agudelo; Gabriel Parra-Henao; Jorge E Osorio
Journal:  J Trop Med       Date:  2012-12-13
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