Literature DB >> 16768636

Determinants of adherence to methylphenidate and the impact of poor adherence on maternal and family measures.

Susan S F Gau1, Hsin-Yi Shen, Miao-Churn Chou, Ching-Shu Tang, Yen-Nan Chiu, Churn-Shiouh Gau.   

Abstract

OBJECTIVE: The aim of this study was to examine the association between adherence to immediate-release methylphenidate (IR MPH) and maternal psychological distress, parenting style, parent- child relationship, and perceived family support.
METHODS: The sample consisted of 307 children with attention-deficit hyperactivity disorder (ADHD) (271 boys and 36 girls), 6-17 years of age, who had been treated with IR MPH for the past 6 months. The measures included the Chinese Health Questionnaire, Parental Bonding Instrument, Family APGAR, and Home Behaviors of the Social Adjustment Inventory for Children and Adolescents.
RESULTS: Reasons for poor adherence (n = 79; 25.7%) included forgetting medication (72.7%), the medication having no effect (20.0%), and refusing medication (12.7%). Increased age and three-times-daily administration were the major predictors for poor adherence to IR MPH. Poor adherence was associated with increased degree of maternal psychological distress, indifferent parenting, maternal overprotection/control, poor family support, decreased interaction with parents, and increased problems at home.
CONCLUSIONS: Findings indicate that multiple daily dosing of MPH increases the likelihood of poor adherence, particularly in adolescents, and that poor adherence is associated with impaired maternal/family process. Once-daily administration of MPH is necessary to improve adherence and to decrease the possible exacerbation of tense parent-child relationships caused by poor drug adherence.

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Year:  2006        PMID: 16768636     DOI: 10.1089/cap.2006.16.286

Source DB:  PubMed          Journal:  J Child Adolesc Psychopharmacol        ISSN: 1044-5463            Impact factor:   2.576


  41 in total

1.  Adolescents' commitment to continuing psychotropic medication: a preliminary investigation of considerations, contradictions, and correlates.

Authors:  Tally Moses
Journal:  Child Psychiatry Hum Dev       Date:  2011-02

2.  Medication refusal in children with oppositional defiant disorder or conduct disorder and comorbid attention-deficit/hyperactivity disorder: medication history and clinical correlates.

Authors:  Mark Demidovich; David J Kolko; Oscar G Bukstein; Jonathan Hart
Journal:  J Child Adolesc Psychopharmacol       Date:  2011-02-02       Impact factor: 2.576

3.  Problems with oral formulations prescribed to children: a focus group study of healthcare professionals.

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Journal:  Int J Clin Pharm       Date:  2015-07-15

4.  To adhere or not, and what we can do to help.

Authors:  F McNicholas
Journal:  Eur Child Adolesc Psychiatry       Date:  2012-09-04       Impact factor: 4.785

5.  Using Meta-analysis to Compare the Efficacy of Medications for Attention-Deficit/Hyperactivity Disorder in Youths.

Authors:  Stephen V Faraone
Journal:  P T       Date:  2009-12

6.  Relationship Between Attention-Deficit/Hyperactivity Disorder Care and Medication Continuity.

Authors:  William B Brinkman; Rebecca Baum; Kelly J Kelleher; James Peugh; William Gardner; Phil Lichtenstein; Joshua Langberg; Jeffery N Epstein
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2016-02-05       Impact factor: 8.829

7.  Documenting adherence to psychostimulants in children with ADHD.

Authors:  Alice Charach; Amy Gajaria; Anna Skyba; Shirley Chen
Journal:  J Can Acad Child Adolesc Psychiatry       Date:  2008-08

Review 8.  Current issues in pediatric medication adherence.

Authors:  Doreen Matsui
Journal:  Paediatr Drugs       Date:  2007       Impact factor: 3.022

Review 9.  Common Factors in Pediatric Psychiatry: A Review of Essential and Adjunctive Mechanisms of Treatment Outcome.

Authors:  Alessandro S De Nadai; Marc S Karver; Tanya K Murphy; Mark A Cavitt; Jeffrey L Alvaro; Michael Bengtson; Saundra Stock; Andrew C Rakhshani; Eric A Storch
Journal:  J Child Adolesc Psychopharmacol       Date:  2016-04-29       Impact factor: 2.576

Review 10.  Treating attention-deficit/hyperactivity disorder beyond symptom control alone in children and adolescents: a review of the potential benefits of long-acting stimulants.

Authors:  Jan Buitelaar; Rossella Medori
Journal:  Eur Child Adolesc Psychiatry       Date:  2009-10-13       Impact factor: 4.785

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