Literature DB >> 167664

Calcium balance in children treated with diphosphonates.

W S Uttley, N R Belton, J Syme, H Sheppard.   

Abstract

Serial mineral balances have been obtained in 3 children undergoing therapy with EHDP (ethane-1-hydroxy-1, 1-diphosphonate) for diseases involving ectopic calcification. Although clinical outcome was not uniformly satisfactory, all cases showed an overall reduction in calcium balance. This was due to increased faecal excretion of calcium and was most marked after a long duration of therapy. Although these results conflict with reported experience in adults, they are in agreement with published observations of the effects of EHDP on calcium absorption in experimental animals.

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Year:  1975        PMID: 167664      PMCID: PMC1544507          DOI: 10.1136/adc.50.3.187

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  15 in total

1.  Favorable response of calcinosis universalis to edathamil disodium.

Authors:  H DAVIS; P J MOE
Journal:  Pediatrics       Date:  1959-11       Impact factor: 7.124

2.  Further studies on pseudo-hypoparathyroidism: report of four new cases.

Authors:  H ELRICK; F ALBRIGHT; F C BARTTER; A P FORBES; J D REEVES
Journal:  Acta Endocrinol (Copenh)       Date:  1950

3.  Indirect inhibition of the biosynthesis of 1,25-dihydroxycholecalciferol in rats treated with a diphosphonate.

Authors:  L F Hill; G A Lumb; E B Mawer; S W Stanbury
Journal:  Clin Sci       Date:  1973-04       Impact factor: 6.124

4.  Diphosphonates in Paget's disease.

Authors:  R G Russell; R Smith; C Preston; R J Walton; C G Woods
Journal:  Lancet       Date:  1974-05-11       Impact factor: 79.321

5.  Diphosphonates in the treatment of myositis ossificans.

Authors:  C A Bassett; A Donath; F Macagno; R Preisig; H Fleisch; M D Francis
Journal:  Lancet       Date:  1969-10-18       Impact factor: 79.321

6.  Intestinal calcium absorption: concurrent use of oral and intravenous tracers and calculation by the inverse convolution method.

Authors:  J Szymendera; R P Heaney; P D Saville
Journal:  J Lab Clin Med       Date:  1972-04

7.  Editorial: Diphosphonate treatment in bone disease.

Authors:  H Fleisch; J P Bonjour
Journal:  N Engl J Med       Date:  1973-12-27       Impact factor: 91.245

8.  Paget's disease of bone. Experience with a diphosphonate (disodium etidronate) in treatment.

Authors:  R Smith; R G Russell; M C Bishop; C G Woods; M Bishop
Journal:  Q J Med       Date:  1973-04

9.  Pseudohypoparathyroidism: defective excretion of 3',5'-AMP in response to parathyroid hormone.

Authors:  L R Chase; G L Melson; G D Aurbach
Journal:  J Clin Invest       Date:  1969-10       Impact factor: 14.808

10.  Diphosphonates inhibit formation of calcium phosphate crystals in vitro and pathological calcification in vivo.

Authors:  M D Francis; R G Russell; H Fleisch
Journal:  Science       Date:  1969-09-19       Impact factor: 47.728

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  2 in total

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Authors:  R B Thomson; J K Johnson
Journal:  Postgrad Med J       Date:  1986-11       Impact factor: 2.401

2.  Effective parenteral clodronate treatment of a child with severe juvenile idiopathic osteoporosis.

Authors:  Ralph Melchior; Bernard Zabel; Jürgen Spranger; Roland Schumacher
Journal:  Eur J Pediatr       Date:  2004-10-23       Impact factor: 3.183

  2 in total

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