Literature DB >> 16758635

Mechanisms of hepatoprotective effect of preparation containing superlow doses of antibodies to granulocytic colony-stimulating factor.

O I Epstein1, G N Zyuz'kov, N V Sotnikova, L A Stavrova, T I Fomina, T V Vetoshkina, S A Sergeeva, T Yu Dubskaya, A M Dygai, E D Gol'dberg.   

Abstract

The hepatoprotective effects of superlow dose preparation of antibodies to granulocytic CSF were studied on a model of CCl4-induced hepatitis. The preparation exhibited high antiinflammatory and antisclerotic activities determined by stimulation, mobilization, and determined homing of mesenchymal stem cells into damaged liver with subsequent differentiation of these cells into mature hepatocytes.

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Year:  2005        PMID： 16758635     DOI： 10.1007/s10517-006-0034-2

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  1 in total

1.  Specific activity of electron-beam synthesis immobilized hyaluronidase on G-CSF induced mobilization of bone marrow progenitor cells.

Authors:  A M Dygai; G N Zyuz'kov; V V Zhdanov; E V Udut; L A Miroshnichenko; E V Simanina; T Yu Khrichkova; M Yu Minakova; P G Madonov
Journal:  Stem Cell Rev Rep       Date:  2013-04       Impact factor: 5.739
  1 in total

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