Literature DB >> 16751131

A short review of some pharmacological, therapeutic and toxicological properties of praziquantel in man and animals.

Badreldin H Ali1.   

Abstract

Praziquantel is the current drug of choice against many trematodes and cestodes in both man and animals. This article summarizes the main pharmacological, therapeutic and toxicological properties of the drug, especially that have been reported during the last 10 years. In most cases, the effectiveness and safety of the drug have been confirmed, although there are currently concerns about the resistance/decreased effectiveness of the drug to certain Schistosome isolates, and also about the mutagenicity of the drug.

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Year:  2006        PMID： 16751131

Source DB:  PubMed          Journal:  Pak J Pharm Sci        ISSN： 1011-601X            Impact factor:   0.684


  6 in total

Review 1.  Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance.

Authors:  Nuno Vale; Maria João Gouveia; Gabriel Rinaldi; Paul J Brindley; Fátima Gärtner; José M Correia da Costa
Journal:  Antimicrob Agents Chemother       Date:  2017-04-24       Impact factor: 5.191

2.  Biological and immunological activity of new imidazolidines against adult worms of Schistosoma mansoni.

Authors:  Juliana Kelle de Andrade Lemoine Neves; Sandra Paula Sarinho Botelho; Cristiane Moutinho Lagos de Melo; Valéria Rêgo Alves Pereira; Maria do Carmo Alves de Lima; Ivan da Rocha Pitta; Mônica Camelo Pessoa de Azevedo Albuquerque; Suely Lins Galdino
Journal:  Parasitol Res       Date:  2010-05-04       Impact factor: 2.289

3.  Comparison of the in vitro Effects of One-day Exposure to Amodiaquine and Praziquantel on Schistosoma mansoni Adult Worm Pairs.

Authors:  Yoshinori Mitsui
Journal:  Trop Med Health       Date:  2014-04-03

4.  Praziquantel is an effective drug for the treatment of Schistosoma Mansoni infection among school-aged children in Northwest Ethiopia.

Authors:  Addisu Tesfie; Gebeyaw Getnet; Aberham Abere; Gebeyehu Yihenew; Yerega Belete; Melkayehu Kassa; Addisu Gize
Journal:  Trop Med Health       Date:  2020-04-29

5.  Combination therapy using Pentostam and Praziquantel improves lesion healing and parasite resolution in BALB/c mice co-infected with Leishmania major and Schistosoma mansoni.

Authors:  Christopher Khayeka-Wandabwa; Helen Kutima; Venny C S Nyambati; Johnstone Ingonga; Elijah Oyoo-Okoth; Lucy Karani; Bernard Jumba; Kiige Githuku; Christopher O Anjili
Journal:  Parasit Vectors       Date:  2013-08-22       Impact factor: 3.876

Review 6.  Efficacy and safety of anthelmintics tested against Taenia solium cysticercosis in pigs.

Authors:  Ernatus Martin Mkupasi; Chummy Sikalizyo Sikasunge; Helena Aminiel Ngowi; Maria Vang Johansen
Journal:  PLoS Negl Trop Dis       Date:  2013-07-25
  6 in total

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