| Literature DB >> 16740469 |
Carl-Henrik Heldin1, Aristidis Moustakas.
Abstract
Signaling by members of the TGFbeta family is much dependent on the common-mediator Smad4, which forms transcriptionally active complexes with all receptor-activated Smads (R-Smads). New findings demonstrate that transcriptional intermediary factor 1gamma (TIF1gamma) also can bind to R-Smads, as an alternative to Smad4, and mediate different transcriptional effects.Entities:
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Year: 2006 PMID： 16740469 DOI： 10.1016/j.devcel.2006.05.006
Source DB: PubMed Journal: Dev Cell ISSN： 1534-5807 Impact factor: 12.270