Literature DB >> 16739986

The human muscle proteome in aging.

Cecilia Gelfi1, Agnese Vigano, Marilena Ripamonti, Alessandro Pontoglio, Shajna Begum, Maria Antonietta Pellegrino, Bruno Grassi, Roberto Bottinelli, Robin Wait, Paolo Cerretelli.   

Abstract

The aim of the present study was to assess age-dependent changes of proteins in the vastus lateralis muscle of physically active elderly and young subjects by a combination of two-dimensional difference gel electrophoresis, SDS-PAGE and ESI-MS/MS. The differences observed in the elderly group included down-regulation of regulatory myosin light chains, particularly the phosphorylated isoforms, a higher proportion of myosin heavy chain isoforms 1 and 2A, and enhanced oxidative and reduced glycolytic capacity.

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Year:  2006        PMID： 16739986     DOI： 10.1021/pr050414x

Source DB:  PubMed          Journal:  J Proteome Res        ISSN： 1535-3893            Impact factor:   4.466


  53 in total

1.  Effects of old age on human skeletal muscle energetics during fatiguing contractions with and without blood flow.

Authors:  Ian R Lanza; Ryan G Larsen; Jane A Kent-Braun
Journal:  J Physiol       Date:  2007-08-02       Impact factor: 5.182

2.  Aging of the musculoskeletal system: How the loss of estrogen impacts muscle strength.

Authors:  Brittany C Collins; Eija K Laakkonen; Dawn A Lowe
Journal:  Bone       Date:  2019-03-28       Impact factor: 4.398

Review 3.  Age-related decline in actomyosin structure and function.

Authors:  Ewa Prochniewicz; LaDora V Thompson; David D Thomas
Journal:  Exp Gerontol       Date:  2007-07-05       Impact factor: 4.032

4.  Fast-twitch sarcomeric and glycolytic enzyme protein loss in inclusion body myositis.

Authors:  Kenneth C Parker; Sek Won Kong; Ronan J Walsh; Mohammad Salajegheh; Behzad Moghadaszadeh; Anthony A Amato; Remedios Nazareno; Yin Yin Lin; Bryan Krastins; David A Sarracino; Alan H Beggs; Jack L Pinkus; Steven A Greenberg
Journal:  Muscle Nerve       Date:  2009-06       Impact factor: 3.217

5.  Proteomic profiling of skeletal muscle plasticity.

Authors:  Kay Ohlendieck
Journal:  Muscles Ligaments Tendons J       Date:  2012-04-01

6.  Comparative proteomic analysis of the aging soleus and extensor digitorum longus rat muscles using TMT labeling and mass spectrometry.

Authors:  Daniela F S Chaves; Paulo C Carvalho; Diogo B Lima; Humberto Nicastro; Fábio M Lorenzeti; Mário Siqueira-Filho; Sandro M Hirabara; Paulo H M Alves; James J Moresco; John R Yates; Antonio H Lancha
Journal:  J Proteome Res       Date:  2013-09-25       Impact factor: 4.466

7.  Differential skeletal muscle proteome of high- and low-active mice.

Authors:  David P Ferguson; Lawrence J Dangott; Emily E Schmitt; Heather L Vellers; J Timothy Lightfoot
Journal:  J Appl Physiol (1985)       Date:  2014-02-06

8.  Label-free quantitative protein profiling of vastus lateralis muscle during human aging.

Authors:  Laëtitia Théron; Marine Gueugneau; Cécile Coudy; Didier Viala; Astrid Bijlsma; Gillian Butler-Browne; Andrea Maier; Daniel Béchet; Christophe Chambon
Journal:  Mol Cell Proteomics       Date:  2013-11-11       Impact factor: 5.911

Review 9.  Studies of complex biological systems with applications to molecular medicine: the need to integrate transcriptomic and proteomic approaches.

Authors:  Elena Silvestri; Assunta Lombardi; Pieter de Lange; Daniela Glinni; Rosalba Senese; Federica Cioffi; Antonia Lanni; Fernando Goglia; Maria Moreno
Journal:  J Biomed Biotechnol       Date:  2010-10-11

10.  Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes.

Authors:  Hyonson Hwang; Benjamin P Bowen; Natalie Lefort; Charles R Flynn; Elena A De Filippis; Christine Roberts; Christopher C Smoke; Christian Meyer; Kurt Højlund; Zhengping Yi; Lawrence J Mandarino
Journal:  Diabetes       Date:  2009-10-15       Impact factor: 9.461
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