| Literature DB >> 16738942 |
Ludovica Segat1, Daiana Bevilacqua, Michele Boniotto, Luiz C Arraes, Paulo R de Souza, Josè L de Lima Filho, Sergio Crovella.
Abstract
In our study, we identified a polymorphism (C-607A) in the promoter region of the IL-18 gene that shows different frequencies between human immunodeficiency virus (HIV)-1-infected children and healthy controls in a pediatric Brazilian population. The presence of the -607 C allele correlates to HIV-1 infection and confers an increased risk of infection in subjects carrying the single nucleotide polymorphism.Entities:
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Year: 2006 PMID: 16738942 DOI: 10.1007/s00251-006-0104-7
Source DB: PubMed Journal: Immunogenetics ISSN: 0093-7711 Impact factor: 2.846