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Literature DB >> 16736019

Approaches to microRNA discovery.

Eugene Berezikov¹, Edwin Cuppen, Ronald H A Plasterk.

Abstract

MicroRNAs (miRNAs) are noncoding RNAs that can regulate gene expression. Several hundred genes encoding miRNAs have been experimentally identified in animals, and many more are predicted by computational methods. How can new miRNAs be discovered and distinguished from other types of small RNA? Here we summarize current methods for identifying and validating miRNAs and discuss criteria used to define an miRNA.

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Year: 2006 PMID： 16736019 DOI： 10.1038/ng1794

Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330

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Cited

174 in total

Review 1. Evolution of microRNA diversity and regulation in animals.

Authors: Eugene Berezikov
Journal: Nat Rev Genet Date: 2011-11-18 Impact factor: 53.242

2. MicroRNAs: Novel Regulators of the Heart.

Authors: Junjie Xiao; Yi-Han Chen
Journal: J Thorac Dis Date: 2010-03 Impact factor: 2.895

3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs.

Authors: Dereje D Jima; Jenny Zhang; Cassandra Jacobs; Kristy L Richards; Cherie H Dunphy; William W L Choi; Wing Yan Au; Gopesh Srivastava; Magdalena B Czader; David A Rizzieri; Anand S Lagoo; Patricia L Lugar; Karen P Mann; Christopher R Flowers; Leon Bernal-Mizrachi; Kikkeri N Naresh; Andrew M Evens; Leo I Gordon; Micah Luftig; Daphne R Friedman; J Brice Weinberg; Michael A Thompson; Javed I Gill; Qingquan Liu; Tam How; Vladimir Grubor; Yuan Gao; Amee Patel; Han Wu; Jun Zhu; Gerard C Blobe; Peter E Lipsky; Amy Chadburn; Sandeep S Dave
Journal: Blood Date: 2010-08-23 Impact factor: 22.113

Approaches to microRNA discovery.

Review 1. Evolution of microRNA diversity and regulation in animals.

2. MicroRNAs: Novel Regulators of the Heart.

3. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs.

Review 4. Folding and finding RNA secondary structure.

Review 5. The discovery approaches and detection methods of microRNAs.

Review 6. Genome-wide approaches in the study of microRNA biology.

7. A microRNA encoded by Autographa californica nucleopolyhedrovirus regulates expression of viral gene ODV-E25.

Review 8. Potential regulatory functions of microRNAs in the ovary.

9. Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes.

10. Novel and conserved heat-responsive microRNAs in wheat (Triticum aestivum L.).