Literature DB >> 16735293

Projecting the demographic impact of AIDS and the number of people in need of treatment: updates to the Spectrum projection package.

J Stover1, N Walker, N C Grassly, M Marston.   

Abstract

BACKGROUND: In the Joint United Nations Programme on HIV/AIDS (UNAIDS) approach to HIV and AIDS estimates, estimates of adult prevalence produced by the Estimation and Projection Package (EPP) or the Workbook are transferred to Spectrum to estimate the consequences of the HIV/AIDS epidemic, including the number of people living with HIV by age and sex, new infections, AIDS deaths, AIDS orphans, treatment needs, and the impact of treatment on survival.
METHODS: The UNAIDS Reference Group on Estimates, Models and Projections recommends updates to the methodology and assumptions based on the latest research findings and international policy and programme guidelines. The latest update to Spectrum has been used in the 2005 round of global estimates.
RESULTS: Several new features have been added to Spectrum in the past two years. New patterns of the age distribution of prevalence over time are based on the latest survey data. A more detailed treatment of mother to child transmission of HIV is now based on information about current breastfeeding practices, treatment options offered to prevent mother to child transmission (PMTCT), infant feeding options, and the percentage or number of pregnant women accessing PMTCT services. A new section on child survival includes the effects of cotrimoxazole and ART on child survival. Projections can now be calibrated with national survey data. A new set of outputs is provided for all adults over the age of 15 in addition to the traditional 15-49 age group. New outputs are now available to show plausibility bounds and regional estimates for key indicators.
CONCLUSIONS: The latest update to the Spectrum program is intended to incorporate the latest research findings and provide new outputs needed by national and international planners.

Entities:  

Mesh:

Substances:

Year:  2006        PMID: 16735293      PMCID: PMC2576732          DOI: 10.1136/sti.2006.020172

Source DB:  PubMed          Journal:  Sex Transm Infect        ISSN: 1368-4973            Impact factor:   3.519


  22 in total

1.  HIV-1 infection in rural Africa: is there a difference in median time to AIDS and survival compared with that in industrialized countries?

Authors:  Dilys Morgan; Cedric Mahe; Billy Mayanja; J Martin Okongo; Rosemary Lubega; James A G Whitworth
Journal:  AIDS       Date:  2002-03-08       Impact factor: 4.177

2.  Declining HIV prevalence and risk behaviours in Zambia: evidence from surveillance and population-based surveys.

Authors:  K Fylkesnes; R M Musonda; M Sichone; Z Ndhlovu; F Tembo; M Monze
Journal:  AIDS       Date:  2001-05-04       Impact factor: 4.177

3.  Improved methods and assumptions for estimation of the HIV/AIDS epidemic and its impact: Recommendations of the UNAIDS Reference Group on Estimates, Modelling and Projections.

Authors: 
Journal:  AIDS       Date:  2002-06-14       Impact factor: 4.177

4.  A multicenter randomized controlled trial of nevirapine versus a combination of zidovudine and lamivudine to reduce intrapartum and early postpartum mother-to-child transmission of human immunodeficiency virus type 1.

Authors:  Dhayendre Moodley; Jagidesa Moodley; Hoosen Coovadia; Glenda Gray; James McIntyre; Justus Hofmyer; Cheryl Nikodem; David Hall; Maria Gigliotti; Patrick Robinson; Lynette Boshoff; John L Sullivan
Journal:  J Infect Dis       Date:  2003-02-24       Impact factor: 5.226

5.  Single-dose perinatal nevirapine plus standard zidovudine to prevent mother-to-child transmission of HIV-1 in Thailand.

Authors:  Marc Lallemant; Gonzague Jourdain; Sophie Le Coeur; Jean Yves Mary; Nicole Ngo-Giang-Huong; Suporn Koetsawang; Siripon Kanshana; Kenneth McIntosh; Vallop Thaineua
Journal:  N Engl J Med       Date:  2004-07-09       Impact factor: 91.245

6.  Projecting the demographic consequences of adult HIV prevalence trends: the Spectrum Projection Package.

Authors:  J Stover
Journal:  Sex Transm Infect       Date:  2004-08       Impact factor: 3.519

7.  Highly active antiretroviral therapies among HIV-1-infected children in Abidjan, Côte d'Ivoire.

Authors:  Patricia Fassinou; Narcisse Elenga; François Rouet; Rockiath Laguide; Kouakou A Kouakoussui; Marguerite Timite; Stephane Blanche; Philippe Msellati
Journal:  AIDS       Date:  2004-09-24       Impact factor: 4.177

8.  Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial.

Authors:  J Brooks Jackson; Philippa Musoke; Thomas Fleming; Laura A Guay; Danstan Bagenda; Melissa Allen; Clemensia Nakabiito; Joseph Sherman; Paul Bakaki; Maxensia Owor; Constance Ducar; Martina Deseyve; Anthony Mwatha; Lynda Emel; Corey Duefield; Mark Mirochnick; Mary Glenn Fowler; Lynne Mofenson; Paolo Miotti; Maria Gigliotti; Dorothy Bray; Francis Mmiro
Journal:  Lancet       Date:  2003-09-13       Impact factor: 79.321

9.  Late postnatal transmission of HIV-1 in breast-fed children: an individual patient data meta-analysis.

Authors:  Anna Coutsoudis; Francois Dabis; Wafaie Fawzi; Philippe Gaillard; Geert Haverkamp; D Robert Harris; J Brooks Jackson; Valerie Leroy; Nicolas Meda; Philippe Msellati; Marie-Louise Newell; Ruth Nsuati; Jennifer S Read; Stefan Wiktor
Journal:  J Infect Dis       Date:  2004-05-26       Impact factor: 5.226

10.  Declining HIV-1 incidence and associated prevalence over 10 years in a rural population in south-west Uganda: a cohort study.

Authors:  S M Mbulaiteye; C Mahe; J A G Whitworth; A Ruberantwari; J S Nakiyingi; A Ojwiya; A Kamali
Journal:  Lancet       Date:  2002-07-06       Impact factor: 79.321

View more
  59 in total

1.  Survey of children accessing HIV services in a high prevalence setting: time for adolescents to count?

Authors:  Rashida Ferrand; Sara Lowe; Barbra Whande; Lucia Munaiwa; Lisa Langhaug; Frances Cowan; Owen Mugurungi; Diana Gibb; Shungu Munyati; Brian G Williams; Elizabeth L Corbett
Journal:  Bull World Health Organ       Date:  2009-12-16       Impact factor: 9.408

2.  More on the cohort-component model of population projection in the context of HIV/AIDS: A Leslie matrix representation and new estimates.

Authors:  Jason R Thomas; Samuel J Clark
Journal:  Demogr Res       Date:  2011-07-05

3.  HIV infection in older adults in sub-Saharan Africa: extrapolating prevalence from existing data.

Authors:  Joel Negin; Robert G Cumming
Journal:  Bull World Health Organ       Date:  2010-08-27       Impact factor: 9.408

4.  Improved plausibility bounds about the 2005 HIV and AIDS estimates.

Authors:  M Morgan; N Walker; E Gouws; K A Stanecki; J Stover
Journal:  Sex Transm Infect       Date:  2006-06       Impact factor: 3.519

5.  Improving analysis of the size and dynamics of AIDS epidemics.

Authors:  P D Ghys; N Walker; G P Garnett
Journal:  Sex Transm Infect       Date:  2006-06       Impact factor: 3.519

6.  Comparing modelled predictions of neonatal mortality impacts using LiST with observed results of community-based intervention trials in South Asia.

Authors:  Ingrid K Friberg; Zulfiqar A Bhutta; Gary L Darmstadt; Abhay Bang; Simon Cousens; Abdullah H Baqui; Vishwajeet Kumar; Neff Walker; Joy E Lawn
Journal:  Int J Epidemiol       Date:  2010-04       Impact factor: 7.196

7.  Adolescent HIV--cause for concern in Southern Africa.

Authors:  Glenda E Gray
Journal:  PLoS Med       Date:  2010-02-02       Impact factor: 11.069

8.  Spectrum: a model platform for linking maternal and child survival interventions with AIDS, family planning and demographic projections.

Authors:  John Stover; Robert McKinnon; Bill Winfrey
Journal:  Int J Epidemiol       Date:  2010-04       Impact factor: 7.196

9.  Sub-Saharan Africa's mothers, newborns, and children: how many lives could be saved with targeted health interventions?

Authors:  Ingrid K Friberg; Mary V Kinney; Joy E Lawn; Kate J Kerber; M Oladoyin Odubanjo; Anne-Marie Bergh; Neff Walker; Eva Weissman; Mickey Chopra; Robert E Black; Henrik Axelson; Barney Cohen; Hoosen Coovadia; Roseanne Diab; Francis Nkrumah
Journal:  PLoS Med       Date:  2010-06-21       Impact factor: 11.069

10.  Determining a cost effective intervention response to HIV/AIDS in Peru.

Authors:  Robert W Aldridge; David Iglesias; Carlos F Cáceres; J Jaime Miranda
Journal:  BMC Public Health       Date:  2009-09-18       Impact factor: 3.295

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.