Literature DB >> 16733573

Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues.

Steven J Moss1, Isabelle Carletti, Carlos Olano, Rose M Sheridan, Michael Ward, Vidya Math, Mohammad Nur-E-Alam, Alfredo F Braña, Ming Qiang Zhang, Peter F Leadlay, Carmen Méndez, José A Salas, Barrie Wilkinson.   

Abstract

We report the directed biosynthesis of borrelidin analogues and their selective anti-proliferative activity against human cancer cell lines.

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Year:  2006        PMID： 16733573     DOI： 10.1039/b602931k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  10 in total

Review 1.  Progress and challenges in aminoacyl-tRNA synthetase-based therapeutics.

Authors:  Christopher S Francklyn; Patrick Mullen
Journal:  J Biol Chem       Date:  2019-01-22       Impact factor: 5.157

Review 2.  Targeting the unfolded protein response in head and neck and oral cavity cancers.

Authors:  Daniel W Cole; Peter F Svider; Kerolos G Shenouda; Paul B Lee; Nicholas G Yoo; Thomas M McLeod; Sean A Mutchnick; George H Yoo; Randal J Kaufman; Michael U Callaghan; Andrew M Fribley
Journal:  Exp Cell Res       Date:  2019-05-07       Impact factor: 3.905

3.  Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues.

Authors:  Martina Werneburg; Benjamin Busch; Jing He; Martin E A Richter; Longkuan Xiang; Bradley S Moore; Martin Roth; Hans-Martin Dahse; Christian Hertweck
Journal:  J Am Chem Soc       Date:  2010-08-04       Impact factor: 15.419

4.  Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo.

Authors:  Eva Maria Novoa; Noelia Camacho; Anna Tor; Barrie Wilkinson; Steven Moss; Patricia Marín-García; Isabel G Azcárate; José M Bautista; Adam C Mirando; Christopher S Francklyn; Sònia Varon; Miriam Royo; Alfred Cortés; Lluís Ribas de Pouplana
Journal:  Proc Natl Acad Sci U S A       Date:  2014-12-08       Impact factor: 11.205

Review 5.  Harnessing natural product assembly lines: structure, promiscuity, and engineering.

Authors:  Christopher C Ladner; Gavin J Williams
Journal:  J Ind Microbiol Biotechnol       Date:  2015-11-02       Impact factor: 3.346

6.  Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms.

Authors:  Jeanette Woolard; William Vousden; Steven J Moss; Arjun Krishnakumar; Melissa Vr Gammons; David G Nowak; Neil Dixon; Jason Micklefield; Astrid Spannhoff; Mark T Bedford; Matthew A Gregory; Christine J Martin; Peter F Leadlay; Ming Q Zhang; Steven J Harper; David O Bates; Barrie Wilkinson
Journal:  Chem Sci       Date:  2011-02-01       Impact factor: 9.825

7.  Aminoacyl-tRNA synthetase dependent angiogenesis revealed by a bioengineered macrolide inhibitor.

Authors:  Adam C Mirando; Pengfei Fang; Tamara F Williams; Linda C Baldor; Alan K Howe; Alicia M Ebert; Barrie Wilkinson; Karen M Lounsbury; Min Guo; Christopher S Francklyn
Journal:  Sci Rep       Date:  2015-08-14       Impact factor: 4.379

Review 8.  Molecular insights on the biosynthesis of antitumour compounds by actinomycetes.

Authors:  Carlos Olano; Carmen Méndez; José A Salas
Journal:  Microb Biotechnol       Date:  2010-11-18       Impact factor: 5.813

Review 9.  Engineered polyketides: Synergy between protein and host level engineering.

Authors:  Jesus F Barajas; Jacquelyn M Blake-Hedges; Constance B Bailey; Samuel Curran; Jay D Keasling
Journal:  Synth Syst Biotechnol       Date:  2017-09-07

10.  Secreted Threonyl-tRNA synthetase stimulates endothelial cell migration and angiogenesis.

Authors:  Tamara F Williams; Adam C Mirando; Barrie Wilkinson; Christopher S Francklyn; Karen M Lounsbury
Journal:  Sci Rep       Date:  2013       Impact factor: 4.379
  10 in total

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