Literature DB >> 16733519

Spinal cord compression of primary extragonadal giant yolk sac tumor.

A Guzel1, M Tatli, D Belen, H Seckin.   

Abstract

STUDY
DESIGN: Case report.
OBJECTIVE: To report an adult male patient with a primary extragonadal giant yolk sac tumor presenting with acute spinal cord compression.
SETTING: Faculty of Medicine, University of Dicle, Diyarbakir, Turkey.
METHOD: A 31-year-old man was referred to our department with a diagnosis of Pott's disease, a complaint of back pain and gait difficulty for 2 weeks. Neurological examination showed spastic paraparesis and hypoesthesia below the L2 dermatome level. He also had urinary incontinence. Abdominal computed tomography and lumbar magnetic resonance imaging study revealed a giant cystic mass lesion located in the psoas muscle. Posteriorly, the third lumbar vertebral body was destructed and the tumor was compressing the dural sac. A combined anterior and posterior approach was performed. Pathological diagnosis was a yolk sac tumor. RESULT: His neurological status improved during the postoperative course. A chemotherapy protocol was given including bleomycin, etoposide and cisplatin. Five months after the last chemotherapy, he was brought to the emergency unit in sepsis and died despite antibiotherapy.
CONCLUSION: Yolk sac tumor should be considered in young adult male patients presenting with acute paraparesis even without any signs or medical history of a testis tumor. These tumors may be unresectable; however, decompression of neural structures and stabilization of the spine with instrumentation may cause substantial improvement in neurological deficit and pain relief.

Entities:  

Mesh:

Year:  2006        PMID: 16733519     DOI: 10.1038/sj.sc.3101942

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  2 in total

1.  Diagnostic and therapeutic challenges in extragonadal yolk sac tumor with hepatoid differentiation: A case report.

Authors:  Vanja Zeremski; Christian Mawrin; Thomas Fischer; Enrico Schalk
Journal:  Mol Clin Oncol       Date:  2016-11-11

2.  Primary yolk sac tumor arising in the pancreas with hepatic metastasis: a case report.

Authors:  Bo Zhang; Shunliang Gao; Ying Chen; Yulian Wu
Journal:  Korean J Radiol       Date:  2010-06-21       Impact factor: 3.500

  2 in total

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