| Literature DB >> 16732531 |
M Sautour1, T Miyamoto, M-A Lacaille-Dubois.
Abstract
Two new spirostanol saponins ( 1 and 2) were isolated from the roots of Smilax medica, together with the known smilagenin 3-O-beta-D-glucopyranoside (3). Their structures were determined by spectroscopic methods including 1D- and 2D-NMR experiments. Compounds 1 and 2 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (MICs between 6.25 and 50 microg/mL) whereas 3 was inactive.Entities:
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Year: 2006 PMID： 16732531 DOI： 10.1055/s-2006-931582
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352