| Literature DB >> 16723150 |
Thomas M O'Hearn1, Srinivas R Sadda, James D Weiland, Mauricio Maia, Eyal Margalit, Mark S Humayun.
Abstract
Stimulus threshold and response latencies were measured for electrically elicited retinal ganglion cell responses in retina isolated from the eyes of normal and retinal degenerate (rd1) mice. Stimulation of the ganglion cell-side in normal retina yielded a significantly lower mean threshold and shorter latency when compared with stimulation of the photoreceptor side in normal retina. The latency of the ganglion cell-side stimulation in normal retina also proved to be significantly shorter than the latency for stimulation of the ganglion cell side in rd1 retina. Thus both the electrode positioning as well as the health of the retinal tissue play a role in the stimulating current required to elicit a retinal response.Entities:
Mesh：
Year: 2006 PMID： 16723150 DOI： 10.1016/j.visres.2006.03.031
Source DB: PubMed Journal: Vision Res ISSN： 0042-6989 Impact factor: 1.886