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Literature DB >> 16722664

Facile purification of honokiol and its antiviral and cytotoxic properties.

Franck Amblard¹, David Delinsky, Jack L Arbiser, Raymond F Schinazi.

Abstract

A separation of honokiol 1 from the closely structurally related magnolol 2 was developed. Honokiol demonstrated weak activity against HIV-1 in human lymphocytes.

Entities: Chemical Species

Mesh：

Substances：

Year: 2006 PMID： 16722664 PMCID： PMC3195338 DOI： 10.1021/jm060268m

Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446

10 in total

1. Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1.

Authors: R F Schinazi; J P Sommadossi; V Saalmann; D L Cannon; M Y Xie; G C Hart; G A Smith; E F Hahn
Journal: Antimicrob Agents Chemother Date: 1990-06 Impact factor: 5.191

2. Antiviral activities and cellular toxicities of modified 2',3'-dideoxy-2',3'-didehydrocytidine analogues.

Authors: Lieven J Stuyver; Stefania Lostia; Marjorie Adams; Judy S Mathew; Balakrishna S Pai; Jason Grier; Phillip M Tharnish; Yongseok Choi; Youhoon Chong; Hyunah Choo; Chung K Chu; Michael J Otto; Raymond F Schinazi
Journal: Antimicrob Agents Chemother Date: 2002-12 Impact factor: 5.191

3. EDRF-release and Ca+(+)-channel blockade by magnolol, an antiplatelet agent isolated from Chinese herb Magnolia officinalis, in rat thoracic aorta.

Authors: C M Teng; S M Yu; C C Chen; Y L Huang; T F Huang
Journal: Life Sci Date: 1990 Impact factor: 5.037

4. Separation procedures applicable to lignan analysis.

Authors: Jirí Slanina; Zdenĕk Glatz
Journal: J Chromatogr B Analyt Technol Biomed Life Sci Date: 2004-12-05 Impact factor: 3.205

5. Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan.

Authors: Tomoyuki Esumi; Gouki Makado; Haifeng Zhai; Yasuhiro Shimizu; Yasuhide Mitsumoto; Yoshiyasu Fukuyama
Journal: Bioorg Med Chem Lett Date: 2004-05-17 Impact factor: 2.823

6. Isolation and purification of honokiol and magnolol from cortex Magnoliae officinalis by high-speed counter-current chromatography.

Authors: Xiao Wang; Yuqiang Wang; Yanling Geng; Fuwei Li; Chengchao Zheng
Journal: J Chromatogr A Date: 2004-05-21 Impact factor: 4.759

7. Two antiplatelet agents from Magnolia officinalis.

Authors: C M Teng; C C Chen; F N Ko; L G Lee; T F Huang; Y P Chen; H Y Hsu
Journal: Thromb Res Date: 1988-06-15 Impact factor: 3.944

8. Metabolites of orally administered Magnolia officinalis extract in rats and man and its antidepressant-like effects in mice.

Authors: Takahiro Nakazawa; Takaaki Yasuda; Keisuke Ohsawa
Journal: J Pharm Pharmacol Date: 2003-11 Impact factor: 3.765

9. Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo.

Authors: Xianhe Bai; Francesca Cerimele; Masuko Ushio-Fukai; Muhammad Waqas; Paul M Campbell; Baskaran Govindarajan; Channing J Der; Traci Battle; David A Frank; Keqiang Ye; Emma Murad; Wolfgang Dubiel; Gerald Soff; Jack L Arbiser
Journal: J Biol Chem Date: 2003-06-19 Impact factor: 5.157

10. Magnolol and honokiol isolated from Magnolia officinalis protect rat heart mitochondria against lipid peroxidation.

Authors: Y C Lo; C M Teng; C F Chen; C C Chen; C Y Hong
Journal: Biochem Pharmacol Date: 1994-02-09 Impact factor: 5.858

10 in total

16 in total

1. In vitro growth inhibition of human cancer cells by novel honokiol analogs.

Authors: Jyh Ming Lin; A S Prakasha Gowda; Arun K Sharma; Shantu Amin
Journal: Bioorg Med Chem Date: 2012-04-03 Impact factor: 3.641

2. Synthesis, cytotoxicity, and antiviral activities of new neolignans related to honokiol and magnolol.

Authors: Franck Amblard; Baskaran Govindarajan; Benjamin Lefkove; Kimberly L Rapp; Mervi Detorio; Jack L Arbiser; Raymond F Schinazi
Journal: Bioorg Med Chem Lett Date: 2007-06-10 Impact factor: 2.823

Review 3. Use of Polyphenolic Compounds in Dermatologic Oncology.

Authors: Adilson Costa; Michael Yi Bonner; Jack L Arbiser
Journal: Am J Clin Dermatol Date: 2016-08 Impact factor: 7.403

4. Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage.

Authors: Adilson Costa; Gustavo Facchini; Ana Lúcia T A Pinheiro; Michelle S da Silva; Michael Y Bonner; Jack Arbiser; Samara Eberlin
Journal: Int J Dermatol Date: 2017-02-22 Impact factor: 2.736

5. Inhibition of Herpes Simplex Virus-1 Replication by Natural Compound Honokiol.

Authors: Shuai Liu; Long Li; Lingbing Tan; Xiaozhen Liang
Journal: Virol Sin Date: 2019-03-26 Impact factor: 4.327

Review 6. COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?

Authors: Dâmaris Silveira; Jose Maria Prieto-Garcia; Fabio Boylan; Omar Estrada; Yris Maria Fonseca-Bazzo; Claudia Masrouah Jamal; Pérola Oliveira Magalhães; Edson Oliveira Pereira; Michal Tomczyk; Michael Heinrich
Journal: Front Pharmacol Date: 2020-09-23 Impact factor: 5.810

10. Honokiol exerts protective effects on neural myelin sheaths after compressed spinal cord injury by inhibiting oligodendrocyte apoptosis through regulation of ER-mitochondrial interactions.

Authors: Yong Tan; Haijun Yu; Shanquan Sun; Shengwei Gan; Rui Gong; Ke-Jie Mou; Jun Xue; Shiye Xu; Jiangfeng Wu; Lan Ma
Journal: J Spinal Cord Med Date: 2021-04-08 Impact factor: 2.040