OBJECTIVE: The aim of the study was to evaluate if the diagnosis and treatment of uterine cavity abnormalities by hysteroscopy in patients undergoingIVF programme is of any value in improving clinical pregnancy outcome. METHODS:520 patients participated in this prospective randomized study and were classified into two groups. Group I (n = 265) without office hysteroscopy. Group II (n = 255) had office hysteroscopy and was sub classified into Group II a and Group II b. Group II a (n = 160) had normal hysteroscopic findings whereas Group II b (n = 95) had abnormal office hysteroscopy findings, which were corrected at the same time. RESULT: There was no difference in the mean number of oocytes retrieved, fertilization rate, and number of embryos transferred among the patients in different groups. Statistically significant difference was observed in terms of clinical pregnancy rates between Group I and Group II a (26.2 and 44.44%, P < 0.05), and Group I and Group II b (26.2 and 39.55%, P < 0.05), respectively. CONCLUSION:Patients with recurrent IVF embryo transfer failures after normal hysterosalpingography findings should also be reevaluated using hysteroscopy prior to further commencing IVF-embryo transfer cycles in order to enhance the clinical pregnancy rates.
RCT Entities:
OBJECTIVE: The aim of the study was to evaluate if the diagnosis and treatment of uterine cavity abnormalities by hysteroscopy in patients undergoing IVF programme is of any value in improving clinical pregnancy outcome. METHODS: 520 patients participated in this prospective randomized study and were classified into two groups. Group I (n = 265) without office hysteroscopy. Group II (n = 255) had office hysteroscopy and was sub classified into Group II a and Group II b. Group II a (n = 160) had normal hysteroscopic findings whereas Group II b (n = 95) had abnormal office hysteroscopy findings, which were corrected at the same time. RESULT: There was no difference in the mean number of oocytes retrieved, fertilization rate, and number of embryos transferred among the patients in different groups. Statistically significant difference was observed in terms of clinical pregnancy rates between Group I and Group II a (26.2 and 44.44%, P < 0.05), and Group I and Group II b (26.2 and 39.55%, P < 0.05), respectively. CONCLUSION:Patients with recurrent IVF embryo transfer failures after normal hysterosalpingography findings should also be reevaluated using hysteroscopy prior to further commencing IVF-embryo transfer cycles in order to enhance the clinical pregnancy rates.
Authors: Mohan S Kamath; Jan Bosteels; Thomas M D'Hooghe; Srividya Seshadri; Steven Weyers; Ben Willem J Mol; Frank J Broekmans; Sesh Kamal Sunkara Journal: Cochrane Database Syst Rev Date: 2019-04-16
Authors: Janine G Smit; Jenneke C Kasius; Marinus J C Eijkemans; Carolien A M Koks; Ron Van Golde; Jurjen G E Oosterhuis; Annemiek W Nap; Gabrielle J Scheffer; Petra A P Manger; Annemiek Hoek; Mesrure Kaplan; Dick B C Schoot; Arne M van Heusden; Walter K H Kuchenbecker; Denise A M Perquin; Kathrin Fleischer; Eugenie M Kaaijk; Alexander Sluijmer; Jaap Friederich; Joop S E Laven; Marcel van Hooff; Leonie A Louwe; Janet Kwee; Jantien J Boomgaard; Corry H de Koning; Ineke C A H Janssen; Femke Mol; Ben W J Mol; Helen L Torrance; Frank J M Broekmans Journal: BMC Womens Health Date: 2012-08-08 Impact factor: 2.809
Authors: Jan Bosteels; Steffi van Wessel; Steven Weyers; Frank J Broekmans; Thomas M D'Hooghe; M Y Bongers; Ben Willem J Mol Journal: Cochrane Database Syst Rev Date: 2018-12-05