Literature DB >> 16714504

What percentages of patients are suitable for prehospital thrombolysis?

N Castle1, R Owen, R Vincent, N Ineson.   

Abstract

OBJECTIVE: To apply the Joint Royal College Ambulance Liaison Committee (JRCALC) checklist to patients who were deemed eligible for thrombolytic therapy on arrival in an Accident & Emergency Department (A&E) to determine the proportion suitable for prehospital thrombolysis.
DESIGN: Retrospective descriptive analysis.
METHODS: The clinical notes of all patients thrombolysed in an A&E department in a year were reviewed against the JRCALC guidelines for prehospital thrombolysis.
RESULTS: 14.2% of patients eligible for thrombolysis in a district general hospital were deemed suitable for prehospital thrombolysis according to the JRCALC criteria. The most common exclusion criteria were hyper/hypotension (50%), onset of symptoms (pain) >6 h previously (41.7%), or age >75 years (37%). Two or more contraindications to prehospital thrombolysis were present in 63.9% of patients.
CONCLUSION: The JRCALC guidelines are an effective tool for identifying patients with potential contraindications to thrombolysis.

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Mesh:

Year:  2006        PMID: 16714504      PMCID: PMC2564339          DOI: 10.1136/emj.2005.026450

Source DB:  PubMed          Journal:  Emerg Med J        ISSN: 1472-0205            Impact factor:   2.740


  12 in total

1.  Mortality and prehospital thrombolysis for acute myocardial infarction: A meta-analysis.

Authors:  L J Morrison; P R Verbeek; A C McDonald; B V Sawadsky; D J Cook
Journal:  JAMA       Date:  2000 May 24-31       Impact factor: 56.272

2.  Is prehospital thrombolysis for acute myocardial infarction warranted in the urban setting? The case against.

Authors:  D T Stephenson; J W Wardrope; S W Goodacre
Journal:  Emerg Med J       Date:  2002-09       Impact factor: 2.740

3.  Potential impact of interventions to reduce times to thrombolysis.

Authors:  S Goodacre; A-M Kelly; D Kerr
Journal:  Emerg Med J       Date:  2004-09       Impact factor: 2.740

4.  Myocardial Infarction Triage and Intervention Project--phase I: patient characteristics and feasibility of prehospital initiation of thrombolytic therapy.

Authors:  W D Weaver; M S Eisenberg; J S Martin; P E Litwin; S M Shaeffer; M T Ho; P Kudenchuk; A P Hallstrom; M D Cerqueira; M K Copass
Journal:  J Am Coll Cardiol       Date:  1990-04       Impact factor: 24.094

5.  Prehospital thrombolytic therapy in patients with suspected acute myocardial infarction.

Authors: 
Journal:  N Engl J Med       Date:  1993-08-05       Impact factor: 91.245

6.  Management of myocardial infarction: implications for current policy derived from the Nottingham Heart Attack Register.

Authors:  J M Rowley; P Mounser; E A Harrison; A M Skene; J R Hampton
Journal:  Br Heart J       Date:  1992-03

7.  Prehospital selection of patients for thrombolysis by paramedics.

Authors:  K Pitt
Journal:  Emerg Med J       Date:  2002-05       Impact factor: 2.740

8.  Relative importance of emergency medical system transport and the prehospital electrocardiogram on reducing hospital time delay to therapy for acute myocardial infarction: a preliminary report from the Cincinnati Heart Project.

Authors:  D J Kereiakes; W B Gibler; L H Martin; K S Pieper; L C Anderson
Journal:  Am Heart J       Date:  1992-04       Impact factor: 4.749

9.  Prehospital diagnosis and treatment of acute myocardial infarction: a north-south perspective. The Cincinnati Heart Project and the Nashville Prehospital TPA Trial.

Authors:  W B Gibler; D J Kereiakes; E N Dean; L Martin; L Anderson; C W Abbottsmith; J Blanton; D Blanton; J A Morris; C D Gibler
Journal:  Am Heart J       Date:  1991-01       Impact factor: 4.749

10.  The costs and benefits of community thrombolysis for acute myocardial infarction : a decision-analytic model.

Authors:  Luke Vale; Harvey Steffens; Cam Donaldson
Journal:  Pharmacoeconomics       Date:  2004       Impact factor: 4.981

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  1 in total

1.  Is there still a place for emergency department thrombolysis following the introduction of the amended Joint Royal Colleges Ambulance Liaison Committee criteria for thrombolysis?

Authors:  N R Castle; R C Owen; M Hann
Journal:  Emerg Med J       Date:  2007-12       Impact factor: 2.740

  1 in total

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