| Literature DB >> 16714476 |
T Néstor H Masckauchán1, Jan Kitajewski.
Abstract
Wnt growth factors function via Frizzled receptors to affect cellular proliferation, differentiation, apoptosis, and migration. Wnt/Frizzled signaling is now linked to human hereditary disorders with retinal vascular defects, implicating Wnts as angiogenic factors. Here, we discuss Wnts and a novel Frizzled ligand, Norrin, in physiological and pathological angiogenesis.Entities:
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Year: 2006 PMID: 16714476 DOI: 10.1152/physiol.00058.2005
Source DB: PubMed Journal: Physiology (Bethesda) ISSN: 1548-9221