Literature DB >> 167050

Chromatographic-fluorometric analysis of antileprotic sulfones.

J F Murray, G R Gordon, C C Gulledge, J H Peters.   

Abstract

Modifications to the power supply system of a spectrophotofluorometer are described. These modifications stabilize the output of the xenon are lamp and permit the determination of nanogram quantities of antileprotic sulfones. The sulfones are removed from plasma by a single extraction with ethyl acetate, then separated by high-pressure liquid chromatography on silica, and detected in the effluent by their fluorescence. The method is specific, rapid, and reproducible.

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Year:  1975        PMID: 167050     DOI: 10.1016/s0021-9673(00)82748-x

Source DB:  PubMed          Journal:  J Chromatogr


  2 in total

1.  Minimal inhibitory concentration of dapsone for Mycobacterium leprae in rats.

Authors:  J H Peters; G R Gordon; J F Murray; A H Fieldsteel; L Levy
Journal:  Antimicrob Agents Chemother       Date:  1975-11       Impact factor: 5.191

2.  Susceptibility of Mycobacterium leprae to dapsone as a determinant of patient response to acedapsone.

Authors:  L Levy; J H Peters
Journal:  Antimicrob Agents Chemother       Date:  1976-01       Impact factor: 5.191

  2 in total

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