Literature DB >> 16704119

Identification of one peptide which inhibited infectivity of avian infectious bronchitis virus in vitro.

Bo Peng1, Hanyang Chen, Yadi Tan, Meilin Jin, Huanchun Chen, Aizhen Guo.   

Abstract

Purified avian infectious bronchitis virus (IBV) was used to screen a random phage display peptide library. After the fourth panning, 10 positive phages were sequenced and characterized. The phages specifically inhibited IBV infectivity in HeLa cells and blocked IBV haemagglutination. One linear peptide "GSH HRH VHS PFV" from the positive phages with the highest neutralization titer was synthesized and this peptide inhibited IBV infection in HeLa as well. The results may contribute to development of antiviral therapeutics for IBV and studying the determinants for viral and cell interaction.

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Year:  2006        PMID： 16704119      PMCID： PMC7088975          DOI： 10.1007/s11427-006-0158-7

Source DB:  PubMed          Journal:  Sci China C Life Sci        ISSN： 1006-9305


  7 in total

1.  Phage-Displayed Peptides Selected to Bind Envelope Glycoprotein Show Antiviral Activity against Dengue Virus Serotype 2.

Authors:  Carolina de la Guardia; Mario Quijada; Ricardo Lleonart
Journal:  Adv Virol       Date:  2017-09-10

Review 2.  Phage display of combinatorial peptide libraries: application to antiviral research.

Authors:  Guillaume Castel; Mohamed Chtéoui; Bernadette Heyd; Noël Tordo
Journal:  Molecules       Date:  2011-04-26       Impact factor: 4.411

3.  Priming with a DNA vaccine and boosting with an inactivated vaccine enhance the immune response against infectious bronchitis virus.

Authors:  Zicheng Guo; Hongning Wang; Tai Yang; Xue Wang; Dan Lu; Yulin Li; Yi Zhang
Journal:  J Virol Methods       Date:  2010-03-20       Impact factor: 2.014

Review 4.  Phage Display Technique as a Tool for Diagnosis and Antibody Selection for Coronaviruses.

Authors:  Taruna Anand; Nitin Virmani; Bidhan C Bera; Rajesh K Vaid; Medhavi Vashisth; Priyanka Bardajatya; Ashok Kumar; Bhupendra N Tripathi
Journal:  Curr Microbiol       Date:  2021-03-09       Impact factor: 2.188

Review 5.  Antiviral peptides against Coronaviridae family: A review.

Authors:  Hamid Heydari; Reza Golmohammadi; Reza Mirnejad; Hamid Tebyanian; Mahdi Fasihi-Ramandi; Mehrdad Moosazadeh Moghaddam
Journal:  Peptides       Date:  2021-03-04       Impact factor: 3.867

Review 6.  Discovery of Antivirals Using Phage Display.

Authors:  Esen Sokullu; Marie-Soleil Gauthier; Benoit Coulombe
Journal:  Viruses       Date:  2021-06-10       Impact factor: 5.048

7.  The immunoreactivity of a chimeric multi-epitope DNA vaccine against IBV in chickens.

Authors:  Lang Tian; Hong-ning Wang; Dan Lu; Yun-fei Zhang; Ting Wang; Run-ming Kang
Journal:  Biochem Biophys Res Commun       Date:  2008-10-07       Impact factor: 3.575
  7 in total

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